RESUMO
The current case highlights an uncommon cause of recurrent pneumonia. A 76 year old female presented to her primary care physician multiple times with recurrent left lower lobe pneumonia. After multiple chest radiographs continued to show no improvement despite antibiotics, a CT of the chest was performed and showed an intraluminal lesion in the left lower lobe bronchus. An endoscopic biopsy was performed and showed the lesion to be a hamartoma. The patient subsequently underwent resection of the lesion and her symptoms resolved. This case illustrates the need for further diagnostic testing when recurrent pneumonia presents with the same lobar distribution.
Assuntos
Broncopatias/diagnóstico , Hamartoma/diagnóstico , Pneumonia/diagnóstico , Idoso , Biópsia , Broncopatias/complicações , Broncopatias/cirurgia , Broncoscopia , Diagnóstico Diferencial , Feminino , Hamartoma/complicações , Humanos , Pneumonia/etiologia , Recidiva , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
The validity of ELISA for detection of E. coli O157:H7 under many conditions is not proven. In this work, sELISA was able to detect bacteria after sub-lethal chlorine exposure and after seven days of starvation with little to no change in limit of detection and fluorescence signal as long as chlorine was not present in the sample or was neutralized by sodium thiosulfate. After Colitag enrichment, sELISA detected approximately 3 colony forming units/ml of originally added E. coli O157:H7. Thus, the present sELISA is valid for detection of E. coli O157:H7 in water sources, although sample matrices may interfere with assay.