Detalhe da pesquisa
1.
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell
; 184(13): 3452-3466.e18, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34139176
2.
Phytocystatin 6 is a context-dependent, tight-binding inhibitor of Arabidopsis thaliana legumain isoform ß.
Plant J
; 116(6): 1681-1695, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37688791
3.
inSPIRE: An Open-Source Tool for Increased Mass Spectrometry Identification Rates Using Prosit Spectral Prediction.
Mol Cell Proteomics
; 21(12): 100432, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280141
4.
iBench: A ground truth approach for advanced validation of mass spectrometry identification method.
Proteomics
; 23(2): e2200271, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36189881
5.
Protease allergens as initiators-regulators of allergic inflammation.
Allergy
; 78(5): 1148-1168, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36794967
6.
Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition.
J Biol Chem
; 295(37): 13047-13064, 2020 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32719006
7.
Structural Alterations of Antigens at the Material Interface: An Early Decision Toolbox Facilitating Safe-by-Design Nanovaccine Development.
Int J Mol Sci
; 22(19)2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34639235
8.
ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease.
Anal Chem
; 92(4): 2961-2971, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31951383
9.
Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family.
Curr Allergy Asthma Rep
; 20(7): 25, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32430735
10.
Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity.
Allergy
; 74(12): 2382-2393, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31230350
11.
Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification.
Bioorg Med Chem
; 25(6): 1889-1900, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215783
12.
Endolysosomal Degradation of Allergenic Ole e 1-Like Proteins: Analysis of Proteolytic Cleavage Sites Revealing T Cell Epitope-Containing Peptides.
Int J Mol Sci
; 18(8)2017 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28812992
13.
Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.
Int J Mol Sci
; 18(10)2017 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29035299
14.
The House Dust Mite Major Allergen Der p 23 Displays O-Glycan-Independent IgE Reactivities but No Chitin-Binding Activity.
Int Arch Allergy Immunol
; 168(3): 150-60, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26797104
15.
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing.
Nat Commun
; 15(1): 1147, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326304
16.
In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.
Front Immunol
; 11: 1824, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33013833
17.
Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation.
Mol Immunol
; 116: 140-150, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31654938
18.
Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Eur J Med Chem
; 179: 765-778, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31284086
19.
Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations.
ACS Catal
; 7(9): 5585-5593, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28932620
20.
Mutagenesis and functional analysis of the pore-forming toxin HALT-1 from Hydra magnipapillata.
Toxins (Basel)
; 7(2): 407-22, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25654788