Detalhe da pesquisa
1.
Design and Evaluation of PROTACs Targeting Acyl Protein Thioesterase 1.
Chembiochem
; 25(4): e202300736, 2024 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195841
2.
Merging the Isonitrile-Tetrazine (4+1) Cycloaddition and the Ugi Four-Component Reaction into a Single Multicomponent Process.
Angew Chem Int Ed Engl
; 62(44): e202311186, 2023 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37682023
3.
Unlocking the Potential of Bio-Based Nitrogen-Rich Furanic Platforms as Biomass Synthons.
Angew Chem Int Ed Engl
; 62(28): e202304449, 2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142557
4.
Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents.
J Am Chem Soc
; 144(23): 10396-10406, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658467
5.
A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening.
Bioprocess Biosyst Eng
; 44(1): 209-215, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816073
6.
Structural insights into TRPV2 activation by small molecules.
Nat Commun
; 13(1): 2334, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484159
7.
Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo.
Cell Mol Bioeng
; 15(3): 231-243, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35611166
8.
Selective Inhibition of Bruton's Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors.
ACS Pharmacol Transl Sci
; 5(11): 1156-1168, 2022 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36407952
9.
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
ACS Cent Sci
; 7(5): 868-881, 2021 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079902
10.
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors.
RSC Chem Biol
; 1(4): 251-262, 2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458764