Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
1.
MMWR Morb Mortal Wkly Rep ; 72(5253): 1385-1389, 2024 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-38175804

RESUMO

During July 7-11, 2023, CDC received reports of two patients in different states with a tuberculosis (TB) diagnosis following spinal surgical procedures that used bone allografts containing live cells from the same deceased donor. An outbreak associated with a similar product manufactured by the same tissue establishment (i.e., manufacturer) occurred in 2021. Because of concern that these cases represented a second outbreak, CDC and the Food and Drug Administration worked with the tissue establishment to determine that this product was obtained from a donor different from the one implicated in the 2021 outbreak and learned that the bone allograft product was distributed to 13 health care facilities in seven states. Notifications to all seven states occurred on July 12. As of December 20, 2023, five of 36 surgical bone allograft recipients received laboratory-confirmed TB disease diagnoses; two patients died of TB. Whole-genome sequencing demonstrated close genetic relatedness between positive Mycobacterium tuberculosis cultures from surgical recipients and unused product. Although the bone product had tested negative by nucleic acid amplification testing before distribution, M. tuberculosis culture of unused product was not performed until after the outbreak was recognized. The public health response prevented up to 53 additional surgical procedures using allografts from that donor; additional measures to protect patients from tissue-transmitted M. tuberculosis are urgently needed.


Assuntos
Mycobacterium tuberculosis , Tuberculose , Humanos , Estados Unidos/epidemiologia , Tuberculose/epidemiologia , Tuberculose/diagnóstico , Mycobacterium tuberculosis/genética , Doadores de Tecidos , Surtos de Doenças , Aloenxertos
2.
Matern Child Nutr ; 12(2): 193-204, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25536083

RESUMO

Pregnancy and lactation are a time when adequate calcium consumption is essential for the development of the fetus and to ensure the health of the mother. Over 50% of Canadian women of childbearing and rearing age fail to meet the recommended daily intake of calcium. Identification of effective behavioural intervention strategies for increasing calcium intake is needed within this specific population. This paper brings together all published behavioural interventions designed to increase calcium consumption in pregnant, lactating or post-partum mothers in a systematic review. Relevant studies were obtained through searches of MEDLINE, EMBASE, PsycINFO, CINAHL and the Cochrane Library with no date restrictions. Studies were evaluated using previously published criteria for evaluating calcium behaviour change interventions. This systematic literature review identified five behavioural calcium interventions conducted within this population. Three interventions aimed to improve overall dietary behaviours, the fourth aimed to promote breastfeeding (including increasing calcium consumption) and the fifth aimed to increase daily servings of yoghurt. Only one of the five interventions yielded large effect sizes, with a mean change of 954 mg of calcium per day post-intervention. The number of behavioural change techniques did not appear to be related to intervention efficacy. Only one study used a theoretical framework to guide the intervention. This review highlights the lack of research examining behaviour change interventions aimed at increasing calcium consumption in pregnant, lactating and post-partum women and provides practical suggestions for researchers wishing to intervene with this population in the future.


Assuntos
Cálcio da Dieta/administração & dosagem , Educação em Saúde/métodos , Adulto , Aleitamento Materno , Canadá , Dieta/estatística & dados numéricos , Feminino , Humanos , Lactação/fisiologia , MEDLINE , Fenômenos Fisiológicos da Nutrição Materna , Pessoa de Meia-Idade , Política Nutricional , Gravidez
3.
Ann Epidemiol ; 74: 111-117, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-35868614

RESUMO

PURPOSE: Examine the joint effect of cognitive function and C-reactive protein (CRP) on all-cause mortality risk in older U.S. adults. METHODS: Sample included 1335 older adult (≥60 years of age) participants in the 1999-2002 National Health and Nutrition Examination Survey. A four-level variable was created using cognitive function and CRP concentration. Mortality was assessed using National Center for Health Statistics linked death records from the National Death Index. RESULTS: Increased risk of all-cause mortality was revealed in adults with high CRP and low cognitive function and in those with low to average CRP and low cognitive function (P < .0001 for both). Sex-stratified analyses revealed increased all-cause mortality risk in males with low cognitive function, independent of CRP concentration. However, in females, a significant increase in all-cause mortality risk was only observed in those with low to average CRP and low cognitive function. CONCLUSIONS: Low cognitive function was associated with increased all-cause mortality risk independent of CRP concentration. However, the joint effect of cognitive function and CRP on all-cause mortality risk differed according to sex.


Assuntos
Proteína C-Reativa , Cognição , Disfunção Cognitiva , Idoso , Biomarcadores/sangue , Proteína C-Reativa/análise , Cognição/fisiologia , Disfunção Cognitiva/sangue , Disfunção Cognitiva/mortalidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais , Fatores de Risco
4.
Popul Health Manag ; 23(5): 350-360, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32897820

RESUMO

Given the severe and rapid impact of COVID-19, the pace of information sharing has been accelerated. However, traditional methods of disseminating and digesting medical information can be time-consuming and cumbersome. In a pilot study, the authors used social listening to quickly extract information from social media channels to explore what people with COVID-19 are talking about regarding symptoms and disease progression. The goal was to determine whether, by amplifying patient voices, new information could be identified that might have been missed through other sources. Two data sets from social media groups of people with or presumed to have COVID-19 were analyzed: a Facebook group poll, and conversation data from a Reddit group including detailed disease natural history-like posts. Content analysis and a customized analytics engine that incorporates machine learning and natural language processing were used to quickly identify symptoms mentioned. Key findings include more than 20 symptoms in the data sets that were not listed in online lists of symptoms from 4 respected medical information sources. The disease natural history-like posts revealed that people can experience symptoms for many weeks and that some symptoms change over time. This study demonstrates that social media can offer novel insights into patient experiences as a source of real-world data. This inductive research approach can quickly generate descriptive information that can be used to develop hypotheses and new research questions. Also, the method allows rapid assessments of large numbers of social media conversations that could be applied to monitor public health for emerging and rapidly spreading diseases such as COVID-19.


Assuntos
Infecções por Coronavirus/fisiopatologia , Progressão da Doença , Disseminação de Informação/métodos , Informática Médica/estatística & dados numéricos , Pandemias/estatística & dados numéricos , Pneumonia Viral/fisiopatologia , Mídias Sociais/estatística & dados numéricos , COVID-19 , Infecções por Coronavirus/epidemiologia , Análise de Dados , Feminino , Humanos , Masculino , Projetos Piloto , Pneumonia Viral/epidemiologia , Saúde Pública , Índice de Gravidade de Doença , Estados Unidos
5.
PM R ; 4(11): 894-900, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23174556

RESUMO

This review article provides an overview of the evidence that links exercise and sports participation to physical and psychological well-being among people with spinal cord injury. Two aspects of physical well-being are examined, including the prevention of chronic disease and the promotion of physical fitness. Multiple aspects of psychosocial well-being are discussed, including mental health, social participation, and life satisfaction. The review concludes with future research recommendations and a discussion of challenges and opportunities for using exercise and sports to promote health and well-being among people living with spinal cord injury.


Assuntos
Pessoas com Deficiência , Exercício Físico/fisiologia , Traumatismos da Medula Espinal/fisiopatologia , Traumatismos da Medula Espinal/psicologia , Esportes , Atividades Cotidianas , Composição Corporal/fisiologia , Densidade Óssea/fisiologia , Doenças Cardiovasculares/prevenção & controle , Diabetes Mellitus/prevenção & controle , Pessoas com Deficiência/psicologia , Humanos , Saúde Mental , Força Muscular/fisiologia , Obesidade/prevenção & controle , Aptidão Física/fisiologia , Qualidade de Vida , Participação Social
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA