Detalhe da pesquisa
1.
VALOR-CKD: A Multicenter, Randomized, Double-Blind Placebo-Controlled Trial Evaluating Veverimer in Slowing Progression of CKD in Patients with Metabolic Acidosis.
J Am Soc Nephrol
; 35(3): 311-320, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261535
2.
Design and population of the VALOR-CKD study: a multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of veverimer in slowing progression of chronic kidney disease in patients with metabolic acidosis.
Nephrol Dial Transplant
; 38(6): 1448-1458, 2023 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36331426
3.
Assessment of the Potential for Veverimer Drug-Drug Interactions.
Drug Metab Dispos
; 49(7): 490-500, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031138
4.
Veverimer versus placebo in patients with metabolic acidosis associated with chronic kidney disease: a multicentre, randomised, double-blind, controlled, phase 3 trial.
Lancet
; 393(10179): 1417-1427, 2019 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30857647
5.
Long-term safety and efficacy of veverimer in patients with metabolic acidosis in chronic kidney disease: a multicentre, randomised, blinded, placebo-controlled, 40-week extension.
Lancet
; 394(10196): 396-406, 2019 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31248662
6.
Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors.
N Engl J Med
; 372(3): 211-21, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415805
7.
Treatment with patiromer decreases aldosterone in patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors.
Kidney Int
; 90(3): 696-704, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27350174
8.
Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia.
Kidney Int
; 88(6): 1427-1433, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26376130
9.
Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.
JAMA
; 314(2): 151-61, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26172895
10.
Randomized trial of an inhibitor of secretory phospholipase A2 on atherogenic lipoprotein subclasses in statin-treated patients with coronary heart disease.
Eur Heart J
; 32(8): 999-1005, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21081550
11.
Effects of 1-H-indole-3-glyoxamide (A-002) on concentration of secretory phospholipase A2 (PLASMA study): a phase II double-blind, randomised, placebo-controlled trial.
Lancet
; 373(9664): 649-58, 2009 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19231633
12.
noxin, a novel stress-induced gene involved in cell cycle and apoptosis.
Mol Cell Biol
; 27(15): 5430-44, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17515607
13.
Randomized, Controlled Trial of TRC101 to Increase Serum Bicarbonate in Patients with CKD.
Clin J Am Soc Nephrol
; 13(1): 26-35, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29102959
14.
Effect of patiromer on reducing serum potassium and preventing recurrent hyperkalaemia in patients with heart failure and chronic kidney disease on RAAS inhibitors.
Eur J Heart Fail
; 17(10): 1057-65, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26459796
15.
Essential function of nitric oxide synthase in Drosophila.
Curr Biol
; 14(20): R881-2, 2004 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15498477
16.
Effects of varespladib methyl on biomarkers and major cardiovascular events in acute coronary syndrome patients.
J Am Coll Cardiol
; 56(14): 1079-88, 2010 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20863951
17.
Neuronal nitric oxide synthase contributes to the regulation of hematopoiesis.
Mol Med
; 14(3-4): 141-9, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18091979
18.
Regulation of multimers via truncated isoforms: a novel mechanism to control nitric-oxide signaling.
Genes Dev
; 18(15): 1812-23, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15256486
19.
Nitric oxide negatively regulates mammalian adult neurogenesis.
Proc Natl Acad Sci U S A
; 100(16): 9566-71, 2003 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12886012