Detalhe da pesquisa
1.
Synthesis and Inhibitor Effect Novel Alkoxymethyl Derivatives of Dihetero Cycloalkanes on Carbonic Anhydrase and Acetylcholinesterase.
Chem Biodivers
; 21(6): e202400296, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38575390
2.
New Azo Derivative of ß-Diketones and Its Cu(II), Co(II) Complexes: Synthesis, Theoretical Study and Biological Activity.
Chem Biodivers
; 21(4): e202301861, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367267
3.
Novel cyclic thiourea derivatives of aminoalcohols at the presence of AlCl3 catalyst as potent α-glycosidase and α-amylase inhibitors: Synthesis, characterization, bioactivity investigation and molecular docking studies.
Bioorg Chem
; 104: 104216, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911191
4.
Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies.
Bioorg Chem
; 99: 103762, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32224335
5.
Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibition properties.
Bioorg Chem
; 103: 104171, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32891857
6.
N-Substituted pyrimidinethione and acetophenone derivatives as a new therapeutic approach in diabetes.
Arch Pharm (Weinheim)
; 353(9): e2000075, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32537841
7.
Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies.
Bioorg Chem
; 93: 103313, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586711
8.
Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials.
Arch Pharm (Weinheim)
; 352(2): e1800317, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600532
9.
Synthesis, characterization, antioxidant, antidiabetic, anticholinergic, and antiepileptic properties of novel N-substituted tetrahydropyrimidines based on phenylthiourea.
J Biochem Mol Toxicol
; 32(12): e22221, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30291660
10.
Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes inhibitors: The novel N,N'-bis-cyanomethylamine and alkoxymethylamine derivatives.
J Biochem Mol Toxicol
; 32(4): e22042, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29457667
11.
Novel amides of 1,1-bis-(carboxymethylthio)-1-arylethanes: Synthesis, characterization, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibitory properties.
J Biochem Mol Toxicol
; 32(9): e22191, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29992664
12.
Synthesis, crystal structure and biological evaluation of spectroscopic characterization of Ni(II) and Co(II) complexes with N-salicyloil-N'-maleoil-hydrazine as anticholinergic and antidiabetic agents.
J Biochem Mol Toxicol
; 32(9): e22197, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044035
13.
Synthesis and investigation of the conversion reactions of pyrimidine-thiones with nucleophilic reagent and evaluation of their acetylcholinesterase, carbonic anhydrase inhibition, and antioxidant activities.
J Biochem Mol Toxicol
; 32(2)2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29283199
14.
Synthesis of new cyclic thioureas and evaluation of their metal-chelating activity, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase inhibition profiles.
J Biochem Mol Toxicol
; 31(7)2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117934
15.
Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base.
J Biochem Mol Toxicol
; 31(9)2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28544359
16.
Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors.
J Enzyme Inhib Med Chem
; 32(1): 1174-1182, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28891347
17.
Synthesis and bioactivity of several new hetaryl sulfonamides.
J Enzyme Inhib Med Chem
; 32(1): 137-145, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100082
18.
Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase.
J Enzyme Inhib Med Chem
; 31(6): 1531-9, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050248
19.
Synthesis of N-alkyl (aril)-tetra pyrimidine thiones and investigation of their human carbonic anhydrase I and II inhibitory effects.
J Enzyme Inhib Med Chem
; 31(6): 1192-7, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586381
20.
Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities.
J Enzyme Inhib Med Chem
; 31(sup3): 1-9, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27329935