Detalhe da pesquisa
1.
An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs.
Mol Cell
; 82(18): 3484-3498.e11, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070765
2.
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling.
Nature
; 578(7796): 582-587, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32051588
3.
Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp.
Proc Natl Acad Sci U S A
; 120(14): e2213771120, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36989297
4.
Aspergillomarasmine A inhibits metallo-ß-lactamases by selectively sequestering Zn2.
J Biol Chem
; 297(2): 100918, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34181945
5.
Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus.
J Biol Chem
; 295(24): 8204-8213, 2020 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350117
6.
Peptidoglycomics reveals compositional changes in peptidoglycan between biofilm- and planktonic-derived Pseudomonas aeruginosa.
J Biol Chem
; 295(2): 504-516, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771981
7.
Suppression of ß-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-ß-Lactamase Target and the Antibiotic Partner.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932375
8.
PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.
Nat Chem Biol
; 14(1): 79-85, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29083419
9.
O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport.
PLoS Pathog
; 13(8): e1006558, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827841
10.
In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).
PLoS Pathog
; 13(10): e1006667, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077761
11.
Peptidoglycan Modification by the Catalytic Domain of Streptococcus pneumoniae OatA Follows a Ping-Pong Bi-Bi Mechanism of Action.
Biochemistry
; 57(16): 2394-2401, 2018 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29595955
12.
Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.
Biochemistry
; 57(13): 1949-1953, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29522326
13.
Accumulation of Peptidoglycan O-Acetylation Leads to Altered Cell Wall Biochemistry and Negatively Impacts Pathogenesis Factors of Campylobacter jejuni.
J Biol Chem
; 291(43): 22686-22702, 2016 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474744
14.
Correction: Peptidoglycomics reveals compositional changes in peptidoglycan between biofilm- and planktonic-derived Pseudomonas aeruginosa.
J Biol Chem
; 295(10): 3387, 2020 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144150
15.
Chemical biology of peptidoglycan acetylation and deacetylation.
Bioorg Chem
; 54: 44-50, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24769153
16.
Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes.
Nat Commun
; 15(1): 4036, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740750
17.
Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-ß-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol
; 31(4): 760-775.e17, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402621
18.
Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa.
Nat Microbiol
; 9(3): 763-775, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38336881
19.
A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall.
bioRxiv
; 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577621
20.
Three-Dimensional Structure and Optimization of the Metallo-ß-Lactamase Inhibitor Aspergillomarasmine A.
ACS Omega
; 7(5): 4170-4184, 2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35155911