Detalhe da pesquisa
1.
Synthesis biological evaluation and molecular docking of isatin hybrids as anti-cancer and anti-microbial agents.
J Enzyme Inhib Med Chem
; 39(1): 2288548, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38073431
2.
Peripheral (E)-2-[(4-hydroxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one)]-coordinated phthalocyanines with improved enzyme inhibition properties and photophysicochemical behaviors.
Arch Pharm (Weinheim)
; : e2400209, 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38838335
3.
Synthesis, biological activities, and molecular docking studies of triazolo[4,3-b]triazine derivatives as a novel class of α-glucosidase and α-amylase inhibitors.
Arch Pharm (Weinheim)
; : e2300628, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38501879
4.
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations.
J Biochem Mol Toxicol
; 37(11): e23465, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462216
5.
Novel Quinazolinone Derivatives: Potential Synthetic Analogs for the Treatment of Glaucoma, Alzheimer's Disease and Diabetes Mellitus.
Chem Biodivers
; 20(10): e202301134, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695993
6.
Synthesis, Biological Activity Evaluation and Molecular Docking of Imidazole Derivatives Possessing Hydrazone Moiety.
Chem Biodivers
; 20(6): e202200886, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37132191
7.
Synthesis, Spectroscopic Characterization, Antibacterial Activity, and Computational Studies of Novel Pyridazinone Derivatives.
Molecules
; 28(2)2023 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677736
8.
3D-QSAR, molecular docking, molecular dynamics, and ADME/T analysis of marketed and newly designed flavonoids as inhibitors of Bcl-2 family proteins for targeting U-87 glioblastoma.
J Cell Biochem
; 123(2): 390-405, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34791695
9.
Novel amino acid Schiff base Zn(II) complexes as new therapeutic approaches in diabetes and Alzheimer's disease: Synthesis, characterization, biological evaluation, and molecular docking studies.
J Biochem Mol Toxicol
; 36(3): e22969, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34812557
10.
The Impact of D614G Mutation of SARS-COV-2 on the Efficacy of Anti-viral Drugs: A Comparative Molecular Docking and Molecular Dynamics Study.
Curr Microbiol
; 79(8): 241, 2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35792936
11.
Could pyrimidine derivative be effective against Omicron of SARS-CoV-2?
Bratisl Lek Listy
; 123(7): 505-513, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907057
12.
Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone.
Bioorg Chem
; 114: 105069, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34134033
13.
Synthesis and docking calculations of tetrafluoronaphthalene derivatives and their inhibition profiles against some metabolic enzymes.
Arch Pharm (Weinheim)
; 354(6): e2000409, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33666284
14.
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea.
Arch Pharm (Weinheim)
; 354(4): e2000334, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33300644
15.
Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies.
Bioorg Chem
; 101: 103969, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32474181
16.
Bioactivity and molecular docking studies of some nickel complexes: New analogues for the treatment of Alzheimer, glaucoma and epileptic diseases.
Bioorg Chem
; 101: 104066, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32650180
17.
Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl-based 4-thiazolidinone derivatives.
Arch Pharm (Weinheim)
; 353(1): e1900304, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31777988
18.
Determination of the inhibition profiles of pyrazolyl-thiazole derivatives against aldose reductase and α-glycosidase and molecular docking studies.
Arch Pharm (Weinheim)
; 353(12): e2000118, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32761859
19.
Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies.
Bioorg Chem
; 93: 103313, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586711
20.
Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound.
J Biomol Struct Dyn
; 42(7): 3349-3362, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37194430