Detalhe da pesquisa
1.
EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma.
Nucleic Acids Res
; 50(17): 9814-9837, 2022 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36124657
2.
Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization.
BMC Biol
; 21(1): 98, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37106386
3.
Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.
Proc Natl Acad Sci U S A
; 114(37): 9870-9875, 2017 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28847958
4.
Genetic variation in one-carbon metabolism in relation to genome-wide DNA methylation in breast tissue from heathy women.
Carcinogenesis
; 37(5): 471-480, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961134
5.
Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers.
Mol Carcinog
; 55(10): 1424-37, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26294040
6.
Practical guidelines for the comprehensive analysis of ChIP-seq data.
PLoS Comput Biol
; 9(11): e1003326, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24244136
7.
Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF.
Nucleic Acids Res
; 40(11): 4754-64, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344698
8.
The DBD-α4 helix of EWS::FLI is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma.
bioRxiv
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352344
9.
Seclidemstat blocks the transcriptional function of multiple FET-fusion oncoproteins.
bioRxiv
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38826330
10.
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.
Nat Cell Biol
; 25(2): 285-297, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36658220
11.
Integrative genome-wide chromatin signature analysis using finite mixture models.
BMC Genomics
; 13 Suppl 6: S3, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23134707
12.
DIME: R-package for identifying differential ChIP-seq based on an ensemble of mixture models.
Bioinformatics
; 27(11): 1569-70, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21471015
13.
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.
Mol Cancer Res
; 20(7): 1035-1046, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298000
14.
Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein.
Epigenetics
; 16(4): 405-424, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32842875
15.
Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins.
Mol Cancer Res
; 19(11): 1795-1801, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34465585
16.
The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma.
Oncogene
; 40(29): 4759-4769, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34145397
17.
Comparative study on ChIP-seq data: normalization and binding pattern characterization.
Bioinformatics
; 25(18): 2334-40, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19561022
18.
Therapeutic modulation of the CD47-SIRPα axis in the pediatric tumor microenvironment: working up an appetite.
Cancer Drug Resist
; 3(3): 550-562, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-35582455
19.
Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis.
J Vis Exp
; (160)2020 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32658189
20.
Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis.
Genes Cancer
; 10(1-2): 21-38, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30899417