RESUMO
OBJECTIVE: The potential effects of four interventions to improve iodine intakes of six New Zealand population groups are assessed. DESIGN: A model was developed to estimate iodine intake when (i) bread is manufactured with or without iodized salt, (ii) recommended foods are consumed to augment iodine intake, (iii) iodine supplementation as recommended for pregnant women is taken and (iv) the level of iodization for use in bread manufacture is doubled from 25-65 mg to 100 mg iodine/kg salt. SETTING: New Zealanders have low and decreasing iodine intakes and low iodine status. Predictive modelling is a useful tool to assess the likely impact, and potential risk, of nutrition interventions. SUBJECTS: Food consumption information was sourced from 24 h diet recall records for 4576 New Zealanders aged over 5 years. RESULTS: Most consumers (73-100 %) are predicted to achieve an adequate iodine intake when salt iodized at 25-65 mg iodine/kg salt is used in bread manufacture, except in pregnant females of whom 37 % are likely to meet the estimated average requirement. Current dietary advice to achieve estimated average requirements is challenging for some consumers. Pregnant women are predicted to achieve adequate but not excessive iodine intakes when 150 µg of supplemental iodine is taken daily, assuming iodized salt in bread. CONCLUSIONS: The manufacture of bread with iodized salt and supplemental iodine for pregnant women are predicted to be effective interventions to lift iodine intakes in New Zealand. Current estimations of iodine intake will be improved with information on discretionary salt and supplemental iodine usage.
Assuntos
Iodo/administração & dosagem , Iodo/deficiência , Política Nutricional , Necessidades Nutricionais , Cloreto de Sódio na Dieta/administração & dosagem , Adolescente , Adulto , Pão , Criança , Pré-Escolar , Suplementos Nutricionais , Feminino , Alimentos Fortificados , Humanos , Masculino , Modelos Teóricos , Nova Zelândia/epidemiologia , Valor Preditivo dos Testes , Gravidez , Adulto JovemRESUMO
The salt content of processed foods is important because of the high intake of Na by most New Zealanders. A database of Na concentrations in fifty-eight processed foods was compiled from existing and new data and combined with 24 h diet recall data from two national nutrition surveys (5771 respondents) to derive salt intakes for seven population groups. Mean salt intakes from processed foods ranged from 6.9 g/d for young males aged 19-24 years to 3.5 g/d for children aged 5-6 years. A total of > or = 50 % of children aged 5-6 years, boys aged 11-14 years and young males aged 19-24 years had salt intakes that exceeded the upper limit for Na, calculated as salt (3.2-5.3 g/d), from processed foods only. Bread accounted for the greatest contribution to salt intake for each population group (35-43 % of total salt intake). Other foods that contributed 2 % or more and common across most age groups were sausage, meat pies, pizza, instant noodles and cheese. The Na concentrations of key foods have changed little over the 16-year period from 1987 to 2003 except for corned beef and whole milk that have decreased by 34 and 50 % respectively. Bread is an obvious target for salt reduction but the implication on iodine intake needs consideration as salt is used as a vehicle for iodine fortification of bread.
Assuntos
Cloreto de Sódio na Dieta/metabolismo , Adolescente , Adulto , Envelhecimento/fisiologia , Pão , Criança , Pré-Escolar , Comportamento de Escolha , Feminino , Análise de Alimentos , Manipulação de Alimentos/métodos , Humanos , Masculino , Nova Zelândia , Reprodutibilidade dos Testes , Cloreto de Sódio na Dieta/análise , Adulto JovemRESUMO
Isoflavones present in soy may have risk and benefits to human health. Human gut microflora have been shown to exert metabolic activities on isoflavones, which influences bioavailability and bioactivity. Absorption of isoflavones is likely to occur in the small intestine where there is a diverse range of microfloral species able to hydrolyze conjugated isoflavones, releasing the bioactive aglycone for absorption or further metabolism and reconjugation. The identification of gut microbes that metabolize isoflavone aglycones is not well established. Such information may lead to a better understanding of the bioavailability of isoflavones in functional foods.
Assuntos
Sistema Digestório/microbiologia , Alimentos Orgânicos , Glycine max/química , Isoflavonas/farmacocinética , Disponibilidade Biológica , Humanos , Absorção Intestinal , Mucosa Intestinal/metabolismo , Isoflavonas/administração & dosagemRESUMO
The impact of caffeine from energy drinks occurs against a background exposure from naturally occurring caffeine (coffee, tea, cocoa and foods containing these ingredients) and caffeinated beverages (kola-type soft drinks). Background caffeine exposure, excluding energy drinks, was assessed for six New Zealand population groups aged 15 years and over (n = 4503) by combining concentration data for 53 caffeine-containing foods with consumption information from the 2008/09 New Zealand Adult Nutrition Survey (ANS). Caffeine exposure for those who consumed energy drinks (n = 138) was similarly assessed, with inclusion of energy drinks. Forty-seven energy drink products were identified on the New Zealand market in 2010. Product volumes ranged from 30 to 600 ml per unit, resulting in exposures of 10-300 mg caffeine per retail unit consumed. A small percentage, 3.1%, of New Zealanders reported consuming energy drinks, with most energy drink consumers (110/138) drinking one serving per 24 h. The maximum number of energy drinks consumed per 24 h was 14 (total caffeine of 390 mg). A high degree of brand loyalty was evident. Since only a minor proportion of New Zealanders reported consuming energy drinks, a greater number of New Zealanders exceeded a potentially adverse effect level (AEL) of 3 mg kg(-1) bw day(-1) for caffeine from caffeine-containing foods than from energy drinks. Energy drink consumption is not a risk at a population level because of the low prevalence of consumption. At an individual level, however, teenagers, adults (20-64 years) and females (16-44 years) were more likely to exceed the AEL by consuming energy drinks in combination with caffeine-containing foods.
Assuntos
Bebidas/análise , Cafeína/efeitos adversos , Cafeína/química , Bebidas Energéticas/efeitos adversos , Bebidas Energéticas/análise , Adolescente , Adulto , Idoso , Feminino , Análise de Alimentos , Humanos , Masculino , Pessoa de Meia-Idade , Nova Zelândia , Adulto JovemRESUMO
The mean dietary exposure to the nutrient elements iodine, Fe, Se and Na by eight age-sex groups of the New Zealand population was estimated from foods purchased and prepared as for consumption. A total of 968 samples comprising 121 foods were collected and analysed. Mean daily exposures were calculated from mean concentration levels of the selected nutrients in each food combined with simulated diets for a 25+-year-old male and female, a 19-24-year-old male, a 11-14-year-old boy and girl, a 5-6-year-old child, a 1-3-year-old toddler and a 6-12-month-old infant. Food concentrations and dietary exposures are reported and compared with nutrient reference values (for example, recommended daily intakes, adequate intakes or upper limits). Dietary iodine exposures for all age-sex groups were well below recommended levels and have steadily decreased since 1982, raising concern especially for the physical and mental development of infants and young children. Fe exposures meet the recommended daily intake for the average male and 11-14 year olds but are only about half that recommended for adult females. Se exposure is about 20 % less than optimal for females. Na exposures, excluding discretionary salt, are above the acceptable exposure level for all age-sex groups, and exceed the upper intake limits for 25+-year-old males, 19-24-year-old young males, and 11-14-year-old boys and girls by up to 125 % for an average consumer.
Assuntos
Dieta/estatística & dados numéricos , Micronutrientes/administração & dosagem , Adolescente , Adulto , Criança , Pré-Escolar , Dieta/tendências , Inquéritos sobre Dietas , Ingestão de Energia , Feminino , Análise de Alimentos/métodos , Humanos , Lactente , Iodo/administração & dosagem , Iodo/análise , Ferro da Dieta/administração & dosagem , Ferro da Dieta/análise , Masculino , Micronutrientes/análise , Nova Zelândia , Garantia da Qualidade dos Cuidados de Saúde , Selênio/administração & dosagem , Selênio/análise , Sódio na Dieta/administração & dosagem , Sódio na Dieta/análiseRESUMO
There is concern that insecticides are able to mimic the action of 17beta-estradiol by interaction with the human estrogen receptor. Pyrethroids are commonly used insecticides and several have been assessed for potential endocrine disrupting activity by various methods. It has been noted that some metabolites of pyrethroids, in particular, permethrin and cypermethrin, have chemical structures that are more likely to interact with the cellular estrogen receptor than the parent pyrethroid. For this study permethrin and cypermethrin metabolites 3-(4-hydroxy-3-phenoxy)benzyl alcohol, 3-(4-hydroxy-3-phenoxy)benzoic acid, and N-3-(phenoxybenzoyl)glycine were synthesised, and together with the commercially available 3-phenoxybenzyl alcohol, 3-phenoxybenzaldehyde, and 3-phenoxybenzoic acid, were studied in a recombinant yeast assay expressing human estrogen receptors (YES). Three metabolites, 3-phenoxybenzyl alcohol, 3-(4-hydroxy-3-phenoxy)benzyl alcohol, and 3-phenoxybenzaldehyde, showed estrogenic activity of approximately 10(5) less than that of 17beta-estradiol. No activity was observed in the yeast assay for 3-phenoxybenzoic acid, 3-(4-hydroxy-3-phenoxy)benzoic acid, and N-3-(phenoxybenzoyl)glycine. The results from this study show that pyrethroid metabolites are capable of interacting with the human estrogen receptor, and so might present a risk to human health and environmental well being. The impact would be expected to be small, but still add to the overall environmental xenoestrogen load.
Assuntos
Receptor alfa de Estrogênio/metabolismo , Estrogênios não Esteroides/metabolismo , Permetrina/metabolismo , Resíduos de Praguicidas/metabolismo , Piretrinas/metabolismo , Bioensaio , Poluentes Ambientais/metabolismo , Inseticidas/metabolismo , Saccharomyces cerevisiae/metabolismoRESUMO
Continuing evidence of the feminising effects of xenoestrogens on a range of wildlife species increases the need to assess the human health risk of these estrogen mimics. We have estimated the exposure of New Zealand males, females and young men to a range of naturally occurring and synthetic xenoestrogens found in food. Only estrogenic compounds that act by interaction with the estrogen receptor have been included. Theoretical plasma estrogen activity levels were derived from estrogen exposure estimates and estrogenic potency data. Theoretical plasma levels were compared with published data for specific xenoestrogens. There was surprisingly close agreement. Xenoestrogenicity from dietary intake was almost equally attributed to naturally occurring and synthetic xenoestrogens. Relative contributions for a male, for example were isoflavones (genistein and daidzein) (36%) and bisphenol A (34%) with smaller contributions from alkyl phenols (18%) and the flavonoids (phloretin and kaempferol) (12%). It is suggested that dietary xenoestrogens might have a pharmacological effect on New Zealand males and postmenopausal women, but are unlikely to be significant for pre-menopausal women.