Detalhe da pesquisa
1.
A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans.
Cell
; 147(4): 840-52, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22035958
2.
Hepatic PEMT activity mediates liver health, weight gain, and insulin resistance.
FASEB J
; 33(10): 10986-10995, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31284753
3.
A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.
FASEB J
; 33(4): 5045-5057, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30615497
4.
From masochistic enzymology to mechanistic physiology and disease.
J Biol Chem
; 292(42): 17169-17177, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855256
5.
Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase.
J Lipid Res
; 58(4): 656-667, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28159867
6.
Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle.
Biochim Biophys Acta
; 1861(2): 119-129, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603903
7.
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
Biochim Biophys Acta Biomembr
; 1859(9 Pt B): 1558-1572, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28411170
8.
Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress.
Biochim Biophys Acta
; 1852(12): 2689-99, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26391255
9.
Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.
Biochim Biophys Acta
; 1851(2): 152-62, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25463480
10.
Pioglitazone attenuates hepatic inflammation and fibrosis in phosphatidylethanolamine N-methyltransferase-deficient mice.
Am J Physiol Gastrointest Liver Physiol
; 310(7): G526-38, 2016 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26797396
11.
Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT.
J Lipid Res
; 56(9): 1701-10, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26113536
12.
Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice.
J Lipid Res
; 56(4): 821-35, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25667419
13.
The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism.
J Biol Chem
; 289(27): 18736-51, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24855646
14.
Phospholipid methylation in mammals: from biochemistry to physiological function.
Biochim Biophys Acta
; 1838(6): 1477-87, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24184426
15.
Phosphatidylcholine metabolism and choline kinase in human osteoblasts.
Biochim Biophys Acta
; 1841(6): 859-67, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24583375
16.
Choline kinase beta is required for normal endochondral bone formation.
Biochim Biophys Acta
; 1840(7): 2112-22, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637075
17.
Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice.
J Hepatol
; 62(4): 913-20, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25433161
18.
Choline supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon action.
J Biol Chem
; 288(2): 837-47, 2013 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23179947
19.
Physiological roles of phosphatidylethanolamine N-methyltransferase.
Biochim Biophys Acta
; 1831(3): 626-32, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22877991
20.
Characterization of lipid and lipoprotein metabolism in primary human hepatocytes.
Biochim Biophys Acta
; 1831(2): 387-97, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22951416