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1.
Rev Med Suisse ; 20(859): 230-234, 2024 Jan 31.
Artigo em Francês | MEDLINE | ID: mdl-38299952

RESUMO

Consensus, defined as the position on which most scientists specialized in a given field agree at a given time, is a key aspect in increasing the readability, credibility and, ultimately, the use of scientific knowledge in public (evidence-based health policy). This article presents several methods aiming at developing scientific consensus between experts, such as the conventional or rapid Delphi approach, the nominal group technique, the RAND-UCLA appropriateness method and the consensus development conference. These methods are used to synthesize expert judgements when uncertainties persist in the literature - each with its own specificities in terms of duration, number of steps and expert participants enlisted, as well as the ways in which they are involved.


Le consensus, défini comme la position sur laquelle la plupart des scientifiques spécialistes d'un domaine se mettent d'accord à un moment donné, est un aspect-clé pour augmenter la lisibilité, la crédibilité et in fine l'utilisation des savoirs scientifiques dans les politiques publiques (evidence-based health policy). Cet article présente plusieurs méthodes permettant le développement de consensus entre personnes expertes, telles que l'approche Delphi conventionnelle ou rapide, la technique du groupe nominal, la méthode d'adéquation RAND-UCLA et la conférence de consensus. Ces méthodes permettent la synthèse des jugements experts lorsque des incertitudes persistent dans la littérature ­ chacune avec des spécificités en termes de durée, du nombre d'étapes et de personnes expertes sollicitées, ainsi que des modalités de leur implication.


Assuntos
Política de Saúde , Política Pública , Humanos , Consenso , Julgamento , Conhecimento
2.
Rev Med Suisse ; 19(812): 181-185, 2023 Feb 01.
Artigo em Francês | MEDLINE | ID: mdl-36723643

RESUMO

New disposable electronic cigarettes have arrived on the Swiss market since 2020. Our study, conducted according to the three steps of the Delphi fast-track approach developed at Unisanté, obtained a consensual agreement among French-speaking Switzerland experts on the regulation of these products. Ideally, the panel of experts recommends a sales ban of the product. If this is not possible, a number of aspects should be strictly regulated: taxation, product composition and marketing, and sales and consumption restrictions. These regulations should go further than the current European directive and the future Swiss law. The conclusions will be useful to support and guide political decision making from a public health and environmental perspective.


De nouvelles cigarettes électroniques jetables sont arrivées sur le marché suisse depuis 2020. Notre étude, conduite selon les trois étapes de la démarche Delphi fast-track développée à Unisanté, a obtenu un accord consensuel entre expert-e-s suisses romand-e-s sur la réglementation de ces produits. Dans l'idéal, le panel d'expert-e-s recommande une interdiction de vente du produit. Si cela n'est pas possible, certains aspects doivent être strictement réglementés : taxation, composition des produits et marketing, restrictions de vente et de consommation. Ces réglementations devraient aller plus loin que l'actuelle directive européenne et la future loi suisse. Les conclusions seront utiles pour soutenir et orienter la prise de décision politique dans une perspective de santé publique et environnementale.


Assuntos
Sistemas Eletrônicos de Liberação de Nicotina , Abandono do Hábito de Fumar , Produtos do Tabaco , Humanos , Consenso , Fumar , Comércio
3.
Nanotoxicology ; 17(1): 1-19, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36927342

RESUMO

Nanotechnology applications are fast-growing in many industrial fields. Consequently, health effects of engineered nanomaterials (ENMs) should be investigated. Within the EU-Life project NanoExplore, we developed a harmonized protocol of an international multicenter prospective cohort study of workers in ENM-producing companies. This article describes the development of the protocol, sample size calculation, data collection and management procedures and discusses its relevance with respect to research needs. Within this protocol, workers' ENM exposure will be assessed over four consecutive working days during the initial recruitment campaign and the subsequent follow-up campaigns. Biomonitoring using noninvasive sampling of exhaled breath condensate (EBC), exhaled air, and urine will be collected before and after 4-day exposure monitoring. Both exposure and effect biomarkers, will be quantified along with pulmonary function tests and diagnosed diseases reported using a standardized epidemiological questionnaire available in four languages. Until now, this protocol was implemented at seven companies in Switzerland, Spain and Italy. The protocol is well standardized, though sufficiently flexible to include company-specific conditions and occupational hygiene measures. The recruitment, to date, of 140 participants and collection of all data and samples, enabled us launching the first international cohort of nanotechnology workers. All companies dealing with ENMs could join the NanoExplore Consortium, apply this harmonized protocol and enter in the cohort, concieved as an open cohort. Its protocol meets all requirements of a hypotheses-driven prospective study, which will assess and reassess effects of ENM exposure on workers' health by updating the follow-up of the cohort. New hypothesis could be also considered.


Assuntos
Nanoestruturas , Exposição Ocupacional , Humanos , Estudos Prospectivos , Exposição Ocupacional/análise , Nanotecnologia , Nanoestruturas/toxicidade , Monitoramento Biológico , Estudos Multicêntricos como Assunto
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