Detalhe da pesquisa
1.
Potent broadly neutralizing antibody VIR-3434 controls hepatitis B and D virus infection and reduces HBsAg in humanized mice.
J Hepatol
; 79(5): 1129-1138, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459920
2.
Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo.
Gut
; 71(2): 372-381, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509930
3.
Murine hepatocytes do not support persistence of Hepatitis D virus mono-infection in vivo.
Liver Int
; 41(2): 410-419, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32997847
4.
Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo.
Gut
; 68(1): 150-157, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29217749
5.
Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection.
Gastroenterology
; 154(3): 652-662.e8, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079518
6.
Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.
Gut
; 67(3): 542-552, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28428345
7.
A humanized mouse model of liver fibrosis following expansion of transplanted hepatic stellate cells.
Lab Invest
; 98(4): 525-536, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352225
8.
A novel orally available small molecule that inhibits hepatitis B virus expression.
J Hepatol
; 68(3): 412-420, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079285
9.
Haem oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice.
Liver Int
; 37(8): 1128-1137, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27992676
10.
Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.
J Hepatol
; 64(5): 1033-1040, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26805671
11.
Multiplexing clonality: combining RGB marking and genetic barcoding.
Nucleic Acids Res
; 42(7): e56, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24476916
12.
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection.
J Hepatol
; 63(2): 346-53, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25795587
13.
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism.
Hepatology
; 60(5): 1483-93, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24711282
14.
Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration.
J Hepatol
; 60(3): 500-7, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398036
15.
Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection.
J Hepatol
; 60(3): 538-44, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24280293
16.
The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus.
J Hepatol
; 58(5): 861-7, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246506
17.
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
Hepatology
; 55(3): 685-94, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031488
18.
Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment.
JHEP Rep
; 5(4): 100673, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36908749
19.
Serum HBV pgRNA as a clinical marker for cccDNA activity.
J Hepatol
; 66(2): 460-462, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826059
20.
Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
Gastroenterology
; 140(7): 2074-83, 2083.e1-2, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376046