Detalhe da pesquisa
1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell
; 184(24): 5886-5901.e22, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822784
2.
Action of (R)-sila-venlafaxine and reboxetine to antagonize cisplatin-induced acute and delayed emesis in the ferret.
Toxicol Appl Pharmacol
; 232(3): 369-75, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18675289
3.
Silicon analogues of the nonpeptidic GnRH antagonist AG-045572: syntheses, crystal structure analyses, and pharmacological characterization.
ChemMedChem
; 6(11): 2070-80, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21953839
4.
Trimethylsilylpyrazoles as novel inhibitors of p38 MAP kinase: a new use of silicon bioisosteres in medicinal chemistry.
Bioorg Med Chem Lett
; 17(2): 354-7, 2007 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17095218
5.
(R)-sila-venlafaxine: a selective noradrenaline reuptake inhibitor for the treatment of emesis.
Bioorg Med Chem Lett
; 16(9): 2555-8, 2006 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16513343
6.
7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
Bioorg Med Chem Lett
; 12(3): 509-12, 2002 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-11814830
7.
8-Methoxyquinoline-5-carboxamides as PDE4 inhibitors: a potential treatment for asthma.
Bioorg Med Chem Lett
; 12(12): 1613-5, 2002 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12039574
8.
8-Methoxyquinolines as PDE4 inhibitors.
Bioorg Med Chem Lett
; 12(12): 1617-9, 2002 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12039575
9.
Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.
J Pharmacol Exp Ther
; 302(1): 127-37, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12065709
10.
Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Bioorg Med Chem Lett
; 12(12): 1621-3, 2002 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12039576