Detalhe da pesquisa
1.
A model for stimulation of enzyme activity by a competitive inhibitor based on the interaction of terazosin and phosphoglycerate kinase 1.
Proc Natl Acad Sci U S A
; 121(9): e2318956121, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38377207
2.
Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage.
Proc Natl Acad Sci U S A
; 121(10): e2318771121, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38416686
3.
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia.
Cell
; 143(6): 911-23, 2010 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145458
4.
Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia.
Nature
; 567(7748): 405-408, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867598
5.
Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs.
Proc Natl Acad Sci U S A
; 119(4)2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35046051
6.
Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs.
Proc Natl Acad Sci U S A
; 119(13): e2121731119, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35324331
7.
The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior.
Cell
; 139(5): 1012-21, 2009 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19945383
8.
Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions.
Proc Natl Acad Sci U S A
; 117(3): 1621-1627, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882447
9.
WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.
Am J Respir Cell Mol Biol
; 67(4): 491-502, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849656
10.
A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis.
Am J Respir Cell Mol Biol
; 66(6): 612-622, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235762
11.
Use of Glycolysis-Enhancing Drugs and Risk of Parkinson's Disease.
Mov Disord
; 37(11): 2210-2216, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054705
12.
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling.
Proc Natl Acad Sci U S A
; 115(6): 1370-1375, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358407
13.
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin.
Am J Physiol Cell Physiol
; 319(2): C331-C344, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32432926
14.
Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH.
J Physiol
; 598(19): 4307-4320, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627187
15.
Gel-forming mucins form distinct morphologic structures in airways.
Proc Natl Acad Sci U S A
; 114(26): 6842-6847, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607090
16.
Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies.
Proc Natl Acad Sci U S A
; 113(19): 5382-7, 2016 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27114540
17.
The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity.
Am J Physiol Lung Cell Mol Physiol
; 315(2): L133-L148, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29631359
18.
Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.
Lab Invest
; 98(6): 825-838, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467455
19.
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung.
Nature
; 487(7405): 109-13, 2012 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22763554
20.
Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.
Am J Respir Crit Care Med
; 195(12): 1617-1628, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28222269