Detalhe da pesquisa
1.
Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
J Biol Chem
; 291(35): 18410-8, 2016 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27365393
2.
Catalytic characterization of human microsomal glutathione S-transferase 2: identification of rate-limiting steps.
Biochemistry
; 52(10): 1755-64, 2013 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23409838
3.
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase.
Nature
; 448(7153): 613-6, 2007 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17632546
4.
Pre-steady-state kinetic characterization of thiolate anion formation in human leukotriene C4 synthase.
Biochemistry
; 51(4): 848-56, 2012 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22217203
5.
Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors.
FASEB J
; 25(4): 1417-27, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228223
6.
Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
J Biol Chem
; 285(52): 40771-6, 2010 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980252
7.
Advances in eicosanoid research, novel therapeutic implications.
Biochem Biophys Res Commun
; 396(1): 135-9, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20494126
8.
Leukotriene B4 triggers release of the cathelicidin LL-37 from human neutrophils: novel lipid-peptide interactions in innate immune responses.
FASEB J
; 21(11): 2897-905, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17446260
9.
High-level expression, purification, and crystallization of recombinant rat leukotriene C(4) synthase from the yeast Pichia pastoris.
Protein Expr Purif
; 60(1): 1-6, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18440824
10.
Structure and catalytic mechanisms of leukotriene A4 hydrolase.
Prostaglandins Other Lipid Mediat
; 83(3): 198-202, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17481555
11.
Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease.
PLoS One
; 7(7): e41786, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22848603
12.
Mutation of a critical arginine in microsomal prostaglandin E synthase-1 shifts the isomerase activity to a reductase activity that converts prostaglandin H2 into prostaglandin F2alpha.
J Biol Chem
; 284(1): 301-305, 2009 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18984580
13.
Synthesis and structure activity relationships of novel non-peptidic metallo-aminopeptidase inhibitors.
Bioorg Med Chem
; 14(21): 7241-57, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16844380
14.
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.
Proc Natl Acad Sci U S A
; 103(21): 8161-6, 2006 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16698924
15.
Fluorescent leukotriene B4: potential applications.
J Lipid Res
; 46(6): 1339-46, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15805550
16.
Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B4 in saliva: effects of treatment with zileuton.
J Allergy Clin Immunol
; 119(5): 1267-8, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17258303