Detalhe da pesquisa
1.
A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Nature
; 556(7699): 103-107, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590091
2.
Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.
Antimicrob Agents Chemother
; 67(4): e0167922, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36943064
3.
Visible-Light/Nickel-Catalyzed Carboxylation of C(sp2) Bromides via Formate Activation.
J Org Chem
; 88(13): 9565-9568, 2023 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37319431
4.
Beyond Ergosterol: Strategies for Combatting Antifungal Resistance in Aspergillus fumigatus and Candida auris.
Tetrahedron
; 1332023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36938356
5.
Exploration of inhibitors of the bacterial LexA repressor-protease.
Bioorg Med Chem Lett
; 65: 128702, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35351585
6.
nTZDpa (non-thiazolidinedione PPARγ partial agonist) derivatives retain antimicrobial activity without improving renal toxicity.
Bioorg Med Chem Lett
; 64: 128678, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35301137
7.
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.
Proc Natl Acad Sci U S A
; 116(33): 16529-16534, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31358625
8.
Building trans-bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development.
Nat Prod Rep
; 38(5): 880-889, 2021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33206093
9.
Trivalent sulfonium compounds (TSCs): Tetrahydrothiophene-based amphiphiles exhibit similar antimicrobial activity to analogous ammonium-based amphiphiles.
Bioorg Med Chem Lett
; 37: 127809, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33516911
10.
Promiscuous Pseudomonas: Uptake of Non-Endogenous Ligands for Iron Acquisition.
Tetrahedron Lett
; 752021 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34248214
11.
Synthesis and biological evaluation of an antibacterial azaborine retinoid isostere.
Tetrahedron Lett
; 622021 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33390617
12.
The histone-like protein AlgP regulon is distinct in mucoid and nonmucoid Pseudomonas aeruginosa and does not include alginate biosynthesis genes.
Microbiology (Reading)
; 166(9): 861-866, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32634088
13.
Analysis of the Destabilization of Bacterial Membranes by Quaternary Ammonium Compounds: A Combined Experimental and Computational Study.
Chembiochem
; 21(10): 1510-1516, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31859426
14.
Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteria.
Bioorg Med Chem Lett
; 30(9): 127099, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171615
15.
A look around the West Indies: The spices of life are secondary metabolites.
Bioorg Med Chem
; 28(23): 115792, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33038665
16.
Total synthesis of (+)-pilosinine via a stereodivergent conjugate addition strategy.
Tetrahedron Lett
; 61(23)2020 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32528190
17.
Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer.
Breast Cancer Res Treat
; 177(2): 369-382, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31254157
18.
From General to Specific: Can Pseudomonas Primary Metabolism Be Exploited for Narrow-Spectrum Antibiotics?
Chembiochem
; 20(1): 34-39, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30088315
19.
Natural Products as Platforms To Overcome Antibiotic Resistance.
Chem Rev
; 117(19): 12415-12474, 2017 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953368
20.
More QACs, more questions: Recent advances in structure activity relationships and hurdles in understanding resistance mechanisms.
Tetrahedron Lett
; 60(37)2019 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32296251