Detalhe da pesquisa
1.
Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages.
Immunity
; 56(1): 162-179.e6, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630914
2.
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells.
Nature
; 610(7930): 161-172, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36171284
3.
The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell-Mediated Killing of AML Leukemic Stem Cells.
Cancer Immunol Res
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38683145
4.
Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.
Eur J Immunol
; 42(10): 2760-70, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22777911
5.
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
Biochem J
; 436(1): 169-79, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21413931
6.
Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.
Biochem J
; 434(2): 265-74, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21204784
7.
Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression.
Cancer Discov
; 11(10): 2638-2657, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33910926
8.
Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers.
Cancer Immunol Res
; 8(1): 131-145, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771984
9.
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Biochem J
; 412(2): 211-21, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18387000
10.
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Mol Cell Biol
; 25(16): 7239-48, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16055732
11.
Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Biochem J
; 405(3): 513-22, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17461779
12.
Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice.
Cancer Immunol Res
; 6(11): 1301-1313, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131378
13.
Vagococcus teuberi sp. nov., isolated from the Malian artisanal sour milk fènè.
Syst Appl Microbiol
; 41(2): 65-72, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29306597
14.
A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics.
Cancer Discov
; 5(12): 1296-313, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446169
15.
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Nat Med
; 19(5): 619-25, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23584089
16.
Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.
Anticancer Res
; 32(2): 415-20, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22287727
17.
How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.
Dis Model Mech
; 4(1): 95-103, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959631
18.
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Mol Cell Biol
; 28(10): 3258-72, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347057
19.
TOR signaling in growth and metabolism.
Cell
; 124(3): 471-84, 2006 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-16469695
20.
Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.
J Cell Sci
; 119(Pt 19): 4059-70, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16968750