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1.
Can J Psychiatry ; : 7067437241255104, 2024 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-38751068

RESUMO

OBJECTIVES: Posttraumatic stress disorder (PTSD) and cannabis use disorder (CUD) commonly co-occur. Conditioned associations between psychological trauma cues, distress, cannabis use, and desired relief outcomes may contribute to the comorbidity. These conditioned associations can be studied experimentally by manipulating trauma cue exposure in a cue-reactivity paradigm (CRP) and examining effects on affective and cognitive outcomes in participants with and without PTSD. However, traditional CRPs take place in-lab limiting recruitment/power. We aimed to examine the effects of CRP condition (trauma and neutral) and PTSD group (likely PTSD+ and PTSD-) on affective and craving outcomes using a stand-alone online expressive writing CRP. METHODS: Participants (n = 202; 43.6% male; Mage = 42.94 years, SD = 14.71) with psychological trauma histories and past-month cannabis use completed a measure of PTSD symptoms (PTSD Checklist-5 for DSM-5 [PCL-5]) and were randomized to complete either a trauma or neutral expressive writing task. Then they completed validated measures of affect (Positive and Negative Affect Schedule-Short Form [PANAS-SF]) and cannabis craving (Marijuana Craving Questionnaire-Short Form [MCQ-SF]). RESULTS: Linear mixed models tested the hypothesized main and interactive effects of CRP condition (trauma and neutral) and PTSD group (likely PTSD+ and PTSD-) on negative and positive affect (PANAS-SF) and cannabis craving dimensions (MCQ-SF). The hypothesized main effects of trauma versus neutral expressive writing were found for negative affect and the expectancy dimension of cannabis craving and of PTSD group for negative affect and all cannabis craving dimensions; no interactions were observed. CONCLUSIONS: Expressive writing appears a useful online CRP. Interventions focused on reducing negative affect and expectancy craving to trauma cues may prevent/treat CUD among cannabis users with PTSD. PLAIN LANGUAGE SUMMARY TITLE: The Use of an Online Expressive Writing as a Trauma Cue Exposure: Effects on Craving and Emotions.


People who have gone through trauma sometimes experience both post-traumatic stress disorder (PTSD) and a tendency to use cannabis excessively (cannabis use disorder or CUD). Researchers believe that there's a connection between traumatic memories, emotional distress, cannabis use, and the relief people feel afterward. These associations can be studied experimentally by using a cue-reactivity paradigm (CRP) to examine effects on craving and affective outcomes in those with and without PTSD. This study included 202 participants who had a history of trauma and reported regular cannabis use. They were randomly assigned to write about a traumatic or neutral personal experience. After, they filled out questionnaires about their PTSD symptoms, emotions (both positive and negative), and cravings for cannabis during the task. We expected that the type of writing task (those assigned to the trauma vs. neutral condition) and PTSD status would be associated with increased cannabis craving, negative emotions, and reduced positive emotions. We found that writing about trauma increased negative feelings and positive expectations about using cannabis for relief, especially for those with PTSD. People with PTSD also seemed to have more ongoing negative feelings and cravings for cannabis. The authors suggest that traditional in-lab experiments might be necessary to fully understand how trauma reminders can influence cravings and emotions in individuals with PTSD-CUD.

2.
J Trauma Stress ; 35(2): 759-770, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-34989449

RESUMO

Parents of children with intellectual and developmental disorders (IDDs) often encounter parenting-related traumatic events. Trauma exposure is a risk factor for mental health problems, including posttraumatic stress disorder (PTSD). Little is known regarding the types of traumatic events that parents commonly experience and how to best assess parenting-related trauma exposure. To address this gap, we developed the Parenting Trauma Checklist (PTC) and tested its psychometric properties. The PTC was created based on an extensive literature review and consultation with stakeholders, which led to the creation of a 17-item instrument. Participants (N = 424) were Canadian parents of children with IDDs who completed an online test battery that included the PTC and several questionnaires to assess PTSD symptoms, global mental and physical health, lifetime trauma exposure, and functional impairment, which were included to test the validity of the new instrument. The PTC demonstrated good construct validity. Ninety four percent of the sample reported parenting-related trauma exposure. Parents reported having experienced an average of 5.79 parenting-related traumatic events, with seeing their child undergo a medical procedure the most frequently endorsed event (68.6%). Experiencing more parenting-related traumatic events was positively associated with higher PTSD symptom levels, r = .35, p < .001. The PTC is a promising instrument that can be used to examine parenting-related trauma exposure. The measure can be used as a screening tool to detect parents' risk of traumatic stress disorders, evaluate traumatic experiences, and assess whether trauma-focused treatment is warranted.


Assuntos
Poder Familiar , Transtornos de Estresse Pós-Traumáticos , Canadá , Lista de Checagem , Criança , Deficiências do Desenvolvimento , Humanos , Poder Familiar/psicologia , Pais , Transtornos de Estresse Pós-Traumáticos/diagnóstico , Transtornos de Estresse Pós-Traumáticos/psicologia
3.
BMC Health Serv Res ; 22(1): 1383, 2022 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-36411458

RESUMO

Caring for children with intellectual and developmental disabilities (IDD) can cause an enormous physical and emotional burden, and therefore these parents have an elevated risk to experience mental health problems. The characteristics of current healthcare systems and parents' responsibilities to care for their children seem to impede their access to mental healthcare. There is so far a lack of instruments to screen for such obstacles. The aim of this study was to develop and validate a scale for measuring barriers to accessing mental healthcare. The Parental Healthcare Barriers Scale (PHBS) was developed on the basis of an extensive literature research, input and discussion from experts and parents with lived experience. A cross-sectional survey was used to collect data from 456 parents of children with IDD. Physical health, mental health, social support, and parenting were measured for concurrent and discriminant validity of the PHBS. The PHBS scale revealed acceptable to good reliability and validity. It consists of four subscales (i.e., support accessibility, personal belief, emotional readiness, and resource availability). The PHBS found parents prioritized their children's treatments over their own mental health challenges (93.4%), did not have enough time (90.4%), and had financial concerns (85.8%). Parents in rural and remote areas had more limited resources. Findings from our study suggest increasing financial support for the parents seeking mental health services, introducing evidence-based treatments, increasing the availability of healthcare services for parents, and adjusting current services to their needs.


Assuntos
Deficiências do Desenvolvimento , Serviços de Saúde Mental , Criança , Humanos , Estudos Transversais , Deficiências do Desenvolvimento/diagnóstico , Deficiências do Desenvolvimento/terapia , Pais/psicologia , Psicometria , Reprodutibilidade dos Testes , Acessibilidade aos Serviços de Saúde , Cuidadores/psicologia
4.
J Gambl Stud ; 31(4): 1135-52, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25112217

RESUMO

Major depression is among the most common comorbid conditions in problem gambling. However, little is known about the effects of comorbid depression on problem gambling. The present study examined the prevalence of current major depression among problem gamblers (N = 105) identified from a community sample of men and women in Alberta, and examined group differences in gambling severity, escape motivation for gambling, family functioning, childhood trauma, and personality traits across problem gamblers with and without comorbid depression. The prevalence of major depression among the sample of problem gamblers was 32.4%. Compared to problem gamblers without depression (n = 71), problem gamblers with comorbid depression (n = 34) reported more severe gambling problems, greater history of childhood abuse and neglect, poorer family functioning, higher levels of neuroticism, and lower levels of extraversion, agreeableness, and conscientiousness. Furthermore, the problem gamblers with comorbid depression had greater levels of childhood abuse and neglect, worse family functioning, higher neuroticism, and lower agreeableness and conscientiousness than a comparison sample of recreational gamblers with depression (n = 160). These findings underscore the need to address comorbid depression in assessment and treatment of problem gambling and for continued research on how problem gambling is related to frequently co-occurring disorders such as depression.


Assuntos
Comportamento Aditivo/epidemiologia , Transtorno Depressivo Maior/epidemiologia , Jogo de Azar/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Adulto , Alberta/epidemiologia , Transtornos de Ansiedade , Comportamento Aditivo/psicologia , Comorbidade , Transtorno Depressivo Maior/psicologia , Feminino , Jogo de Azar/psicologia , Humanos , Masculino , Saúde Mental/estatística & dados numéricos , Pessoa de Meia-Idade , Neuroticismo , Prevalência , Qualidade de Vida/psicologia , Fatores de Risco , Transtornos Relacionados ao Uso de Substâncias/psicologia
5.
Addict Behav ; 142: 107675, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-36857931

RESUMO

BACKGROUND: Polysubstance use, which increases the risk for negative consequences of substance use, is common among emerging adults who regularly consume substances by vaping. Examining predictors of polysubstance vaping is crucial for understanding whether this novel form of substance consumption lends itself equally efficaciously to established forms of intervention for smoked substances. OBJECTIVE: The current study aimed to examine whether modifiable cognitive risk factors for increased vaping in the form of attitudes, expectancies and norms can predict co-use of nicotine and cannabis among vapers over and above the effect of demographics, personality risk factors and anxiety, depression symptoms. METHODS: Regular nicotine and cannabis vapers between 18 and 30 years were recruited online in Canada via a Qualtrics panel. Hierarchical binary logistic regression was used to predict membership in a polysubstance or a single substance vaping group. Demographics, personality risk factors, depression and anxiety symptoms were included as predictors in block 1; attitudes, expectancies and perceived norms of vaping were added in block 2. RESULTS: Attitudes, expectancies and norms predicted polysubstance use over and above the effect of demographics, personality risk factors and anxiety, depression symptoms. Positive expectancies played a uniquely significant role in the prediction of polysubstance vaping. CONCLUSIONS: Cognitive interventions targeting attitudes, expectancies and norms may be effective in prevention of polysubstance vaping, although positive expectancies appear to be the main unique factor that has an influence above and beyond all other cognitive factors related to vaping. Treatment and prevention programs should put special focus on lowering positive expectancies.


Assuntos
Cannabis , Sistemas Eletrônicos de Liberação de Nicotina , Alucinógenos , Vaping , Adulto , Humanos , Vaping/epidemiologia , Vaping/psicologia , Nicotina , Fumantes , Atitude , Fatores de Risco
6.
Front Psychol ; 14: 1018098, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37502746

RESUMO

Introduction: While individuals have many motives to gamble, one particularly risky motive for gambling is to cope with negative affect. Conflict with one's romantic partner is a strong predictor of negative affect, which may elicit coping motives for gambling and, in turn, gambling-related problems. Support for this mediational model was demonstrated in relation to drinking-related problems. We extended this model to gambling. Method: Using a cross-sectional design, we examined links between romantic conflict (Partner-Specific Rejecting Behaviors Scale), negative affect (Depression, Anxiety, and Stress Scales-21), coping gambling motives (Gambling Motives Questionnaire, coping subscale), and gambling-related problems [Problem Gambling Severity Index (PGSI)] in 206 regular gamblers (64% men; mean age = 44.7 years; mean PGSI = 8.7) who were in a romantic relationship and recruited through Qualtrics Panels in July 2021. Results: Results supported our hypothesis that the association between romantic conflict and gambling-related problems would be sequentially mediated through negative affect and coping gambling motives, ß = 0.38, 95% CI [0.27, 0.39], and also showed a strong single mediation pathway through negative affect alone, ß = 0.27, 95% CI [0.17, 0.38]. Discussion: Negative affect and coping gambling motives partially explain the link between romantic conflict and gambling-related problems. Interventions should target both negative affect and coping gambling motives in response to romantic conflict to reduce gambling-related problems in partnered gamblers.

7.
Int J Methods Psychiatr Res ; : e1979, 2023 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-37430485

RESUMO

OBJECTIVES: Derived from classical conditioning theory and rooted in motivational mechanisms, cue reactivity paradigms (CRPs) are used in addictions research to measure participants' propensities for substance-relevant responses (e.g., craving) during exposure to substance-relevant cues (e.g., drug paraphernalia). CRPs are also useful in PTSD-addiction comorbidity research, allowing the study of affective and substance-relevant responses to trauma cues. However, studies using traditional CRPs are time-consuming with high attrition rates due to repeat testing. Thus, we sought to test whether a single session semi-structured trauma interview could serve as a CRP in terms of eliciting theorized cue exposure effects on craving and affect measures. METHOD: Fifty regular cannabis users with trauma histories provided detailed descriptions of their most traumatic lifetime experience, and a neutral experience, according to an established interview protocol. Linear mixed models examined the effect of cue type (trauma vs. neutral) on affective and craving responses. RESULTS: As hypothesized, the trauma interview elicited significantly greater cannabis craving (and alcohol craving among the drinkers), and, greater negative affect among those with more severe PTSD symptoms, compared to the neutral interview. CONCLUSION: Results suggest an established semi-structured interview may function effectively as a CRP for use in trauma and addictions research.

9.
Psychiatry Res ; 326: 115298, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-37327652

RESUMO

Smartphone use provides a significant amount of screen-time for youth, and there have been growing concerns regarding its impact on their mental health. While time spent in a passive manner on the device is frequently considered deleterious, more active engagement with the phone might be protective for mental health. Recent developments in mobile sensing technology provide a unique opportunity to examine behaviour in a naturalistic manner. The present study sought to investigate, in a sample of 451 individuals (mean age 20.97 years old, 83% female), whether the amount of time spent on the device, an indicator of passive smartphone use, would be associated with worse mental health in youth and whether an active form of smartphone use, namely frequent checking of the device, would be associated with better outcomes. The findings highlight that overall time spent on the smartphone was associated with more pronounced internalizing and externalizing symptoms in youth, while the number of unlocks was associated with fewer internalizing symptoms. For externalizing symptoms, there was also a significant interaction between the two types of smartphone use observed. Using objective measures, our results suggest interventions targeting passive smartphone use may contribute to improving the mental health of youth.


Assuntos
COVID-19 , Aplicativos Móveis , Humanos , Feminino , Adolescente , Adulto Jovem , Adulto , Masculino , Smartphone , Saúde Mental , Pandemias
10.
Exp Clin Psychopharmacol ; 30(4): 400-408, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35377694

RESUMO

The use of crowd-sourced and panel survey data in addiction research has become widespread. However, the validity of data obtained from newer panels such as Qualtrics has not been extensively evaluated. Furthermore, few addiction researchers appear to employ previously recommended guidelines for maximizing the quality of data obtained from panel samples. The goals of the present study were as follows: (a) to evaluate the quality of survey data obtained from Qualtrics including an evaluation of the company's internal data screening process and (b) to provide a practical implementation guide for data screening practices that maximize the quality of data obtained via panel and crowd-sourced samples. To address the goals, two panel samples evaluating vaping and video gaming behaviors were recruited in Canada via Qualtrics and underwent Qualtrics's internal data screening process before being rigorously rescreened by the authors. The results demonstrate that while Qualtrics's paid internal data quality process flags and removes many low-quality participants, there is still a large portion of participants presented by Qualtrics as high-quality that are likely low-quality responses that need to be screened out. The presented methodology provides a rigorous data screening protocol, including step-by-step application, for crowd-sourced samples in addictive behavior research for maximizing data quality. Researchers should be cautious in the use of Qualtrics data for administration of addiction survey research and are encouraged to use additional data screening procedures to maximize data quality. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Comportamento Aditivo , Crowdsourcing , Jogos de Vídeo , Comportamento Aditivo/psicologia , Humanos , Inquéritos e Questionários , Jogos de Vídeo/psicologia
11.
Exp Clin Psychopharmacol ; 30(4): 424-431, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35511535

RESUMO

Crowdsourced samples are increasing in popularity, particularly within psychological and addictive behaviors research. The trend has resulted in significant interest in the use of panel samples for the examination of behavioral and substance addictions. One newer panel platform, Qualtrics, has seen an increase in usage in recent years despite lack of research examining the validity of Qualtrics-produced data for addictive behaviors. The goal of the present study was to evaluate the validity of Qualtrics-obtained data for the most recently classified behavioral addiction-video gaming. The evaluation compared a Qualtrics-recruited video gamers sample (n = 586) to traditional community (n = 108) and student (n = 217) samples on demographics and key outcomes relevant to gaming disorder researchers (average playtime, frequency of gaming, and gaming disorder risk scores) to evaluate the generalizability of Qualtrics panel data. The results revealed that Qualtrics samples were comparable to a traditionally recruited community sample, but different from a student sample on gaming frequency (p < .001) and risk for gaming disorder (p < .001). The Qualtrics sample also had longer durations of average gaming time relative to the student sample (p = .01), with some differences in demographics between the all three sources of recruitment. The findings suggest that Qualtrics may provide a suitable method of convenience panel recruitment, generalizable to the broader North American community, for research examining video gaming behaviors and gaming disorder. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Comportamento Aditivo , Jogos de Vídeo , Comportamento Aditivo/psicologia , Humanos , Internet , Motivação , Reprodutibilidade dos Testes , Estudantes , Jogos de Vídeo/psicologia
12.
Mult Scler Relat Disord ; 57: 103338, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35158449

RESUMO

BACKGROUND: Multiple sclerosis (MS) is a chronic demyelinating disease which leads to sensory, motor, autonomic, and cognitive symptoms. Cannabis is a common way for persons with MS (pwMS) to seek symptomatic therapy. Given the capacity for both cannabis and MS to cause cognitive impairment, it is important to determine whether there is any negative impact when the two co-occur. The objective of this systematic review was to evaluate the effects of cannabis and medicinal cannabinoid products on cognition in pwMS in order to provide guidance to clinicians and enable them to make evidence-based recommendations regarding cannabis and cannabinoid products. METHODS: A systematic review was carried out searching common keyword combinations for cannabis and MS across five databases, producing 840 unique articles, 18 of which were included in a qualitative synthesis. RESULTS: Aggregate data from existing studies to date highlight potential impairments from chronic whole-plant cannabis use in commonly affected cognitive domains in multiple sclerosis, including attention and working memory, and to a lesser extent, visual memory, verbal memory, and executive function. Results also suggest that in the short-term, medicinal cannabinoid preparations do not significantly impair cognition and may even ameliorate cognitive symptoms in the context of obtrusive MS disease. The findings are limited by disparities in detail of cannabis use data reported across whole-plant cannabis publications. CONCLUSION: Existing literature on co-occurrence of cannabis use and MS lacks high quality evidence to recommend for or against cannabis and cannabinoid therapies for pwMS based on cognitive effects. Existing data suggest that cognition may be differentially impacted in pwMS depending on the type of product, the duration of use, and the indication. Future studies on whole-plant cannabis require comprehensive cannabis use data reporting including frequency, dosing, duration, and type of cannabis product. Future studies on medicinal cannabinoid products should be long-term to assess the effects of chronicity.


Assuntos
Canabinoides , Cannabis , Esclerose Múltipla , Cognição , Função Executiva , Humanos , Esclerose Múltipla/complicações , Esclerose Múltipla/tratamento farmacológico , Esclerose Múltipla/epidemiologia
13.
Front Psychiatry ; 13: 1018234, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36440391

RESUMO

Sports betting is one of the most popular forms of gambling in Canada; recent prevalence estimates indicate that 7.9% of Canadian adults endorsed gambling on sports in the past year. The ongoing COVID-19 pandemic led to the temporary closure of most major sports leagues worldwide beginning in March of 2020. These sudden closures created a dramatic decrease in the availability of sports betting opportunities in the early stages of the pandemic, followed by a subsequent increase in availability as most sport leagues returned during the summer of 2020. Using a retrospective self-report measure of gambling participation, the present study investigated how the gambling behaviors of N = 85 past-year sports gamblers changed over the course of the pandemic. It was hypothesized that sports gamblers would report an initial decrease in gambling behaviors from pre-pandemic baseline levels to the early stages of the pandemic in May of 2020 when the availability of sports gambling was heavily restricted, followed by an increase in gambling behaviors from May to August, in accordance with the re-emergence of live sporting events. The general pattern of results supported the hypotheses, though gambling behaviors did not completely return to baseline levels. Beyond quantifying the changes in gambling behaviors over the early stages of the pandemic in Canada, results may have implications regarding the utility of voluntary gambling exclusion programs as well as legislation concerning gambling access.

14.
Internet Interv ; 23: 100354, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33425687

RESUMO

Despite evidence for effectiveness, only a small proportion of individuals with gambling disorder ever access treatment and support resources for their problem. Voluntary self-exclusion (VSE) programs are an ideal circumstance to engage individuals who are reluctant or have not yet sought formal treatment, given that individuals are already electing to prevent themselves from gambling through self-exclusion. The present study was a randomized controlled trial of a novel, online VSE self-management intervention. Individuals who chose to self-exclude at gambling venues (N = 201) were randomly assigned to participate in an online self-management program combined with VSE or to an in-person self-awareness educational workshop combined with VSE comparison group. Following a baseline assessment, participants were followed up at three, six, and twelve months via telephone interviews. Measured outcomes were gambling frequency and expenditure, problem gambling scores, problem drinking scores, type of goal set for gambling behaviour, quality of life, and treatment-seeking. The 12-month follow-up rate was 71% (n = 143). Participants in both VSE groups gambled less, spent less money gambling, and reported decreased need for formal treatment. However, there were no significant group differences on any of the primary or secondary outcomes. Only 30-35% of the participants completed their assigned workshop, depending on the group. Results from the online program satisfaction survey revealed that participants generally liked the program and rated the quality of the content highly, but thought there could be improvement regarding interactivity, variety, stimulation and greater clarity around registration steps and program objectives. The online VSE program is an effective alternative to the face-to-face VSE program. Although the outcomes between the two programs were not significantly different, the online program is easier to administer, able to reach more individuals since it only requires access to a computer and is based on motivational evidence-based principles of psychotherapy for gambling disorder.

15.
Addict Behav ; 112: 106567, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32768794

RESUMO

BACKGROUND AND HYPOTHESES: Extant research has not studied whether norm perceptions differ between young adult cannabis users who do and do not meet screening criteria for problematic cannabis use. Drawing on sociocultural norms research on alcohol, we hypothesized that users meeting screening criteria for cannabis problems would be more likely than those not meeting those criteria to (1) mistakenly believe that social reference groups use about the same amount of cannabis as they do, (2) adjust private approval of peer cannabis use to match mistaken public approval norms, and (3) believe that behavioral and social consequences are less definitive of problematic cannabis use. METHODS: Secondary analyses of data from 753 cannabis users recruited from a Canadian university population survey (57% female; M age = 22.58). Parametric and non-parametric ANOVAs examined respondents' perceptions and beliefs regarding the cannabis use of same-sex friends, students, and adults living in the same Canadian province. RESULTS: Contrary to prediction, problematic cannabis users were more likely than non-problematic users to (accurately) believe that social reference groups use cannabis less frequently than themselves. As hypothesized, problematic users were more likely than non-problematic users to adjust private approval of fellow students' cannabis use to match perceived public approval, and to believe that sociobehavioral criteria are less definitive of cannabis problems. CONCLUSION: Results support the need to develop brief interventions to correct misperceptions of (a) injunctive cannabis norms and (b) sociobehavioral criteria that define safe versus problematic use, rather than perceived frequency of use in social reference groups.


Assuntos
Cannabis , Adulto , Canadá , Feminino , Humanos , Masculino , Grupo Associado , Percepção , Estudantes , Universidades , Adulto Jovem
16.
Psychopharmacology (Berl) ; 238(7): 1965-1977, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33813611

RESUMO

RATIONALE: Cannabidiol (CBD) has been reported to attenuate stress and anxiety, but little is known about the extent to which such effects result from pharmacological versus expectancy factors. OBJECTIVES: We evaluated whether CBD expectancy alone could influence stress, anxiety, and mood, and the extent to which beliefs regarding CBD effects predicted these responses. METHODS: In this randomized crossover study, 43 health adults (23 women) attended two experimental laboratory sessions, where they self-administered CBD-free hempseed oil sublingually. During one session, they were (incorrectly) informed that the oil contained CBD and in the other session, that the oil was CBD-free. Following administration, participants engaged in the Maastricht Acute Stress Test (MAST). Heart rate variability (HRV) was assessed continuously, and subjective state was assessed at baseline, 90-min following oil administration, immediately following the MAST, and after a 10-min recovery period. RESULTS: The CBD expectancy condition was associated with increased sedation as well as with changes in HRV that were consistent with heightened anticipatory stress regulation. Overall, there were no systematic changes in subjective stress, or anxiety, according to expectancy condition. However, participants who endorsed strong a priori beliefs that CBD has anxiolytic properties reported significantly diminished anxiety in the CBD expectancy condition. CONCLUSIONS: CBD expectancy alone impacted several subjective and physiological responses. Additionally, expectancy-related factors were implicated in anxiolytic effects of CBD for those who believed it was helpful for such purposes, emphasizing the need to measure and control for CBD-related expectancies in clinical research that involves the administration of CBD.


Assuntos
Ansiedade/tratamento farmacológico , Ansiedade/psicologia , Canabidiol/administração & dosagem , Motivação/efeitos dos fármacos , Estresse Psicológico/tratamento farmacológico , Estresse Psicológico/psicologia , Administração Sublingual , Adulto , Afeto/efeitos dos fármacos , Afeto/fisiologia , Ansiolíticos/administração & dosagem , Estudos Cross-Over , Método Duplo-Cego , Eletrocardiografia/efeitos dos fármacos , Eletrocardiografia/métodos , Feminino , Frequência Cardíaca/efeitos dos fármacos , Frequência Cardíaca/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Motivação/fisiologia , Autoadministração , Adulto Jovem
17.
J Subst Abuse Treat ; 101: 67-71, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31174715

RESUMO

A major complicating factor for hepatitis C virus (HCV) vaccine clinical trial design and implementation is engagement and retention of people who use drugs (PWUD). Informed willingness to participate (WTP) in vaccine trials has emerged as a critical issue to describe, understand, and promote among populations at increased risk of communicable disease incidence. The present study addressed this topic by examining correlates of WTP among 320 socially marginalized PWUD as part of the Edmonton Drug Use and Health Survey (EDUHS). WTP was analyzed in relation to: gender, age, housing stability, ethnicity; self-reported hospital care in the past six months, self-reported injection drug use in the past 6 months, lifetime addiction treatment for alcohol or drugs, severity of drug use problems, and unmet healthcare needs. EDUHS participants reported high rates of current injection drug use (91%), and about two-thirds (67.3%) reported a lifetime HCV positive status. HCV positive respondents were older, had more severe substance use problems, and reported injecting drugs more frequently, compared to HCV negative respondents. Among the subsample of HCV negative respondents, 81% affirmed that they would be willing to enroll in a HCV vaccine prevention trial. Those reporting WTP were more likely to have had a recent hospital admission, to report more total unmet healthcare needs, and greater unmet needs for information, hospital care, and counseling, compared to HCV negative respondents not willing to enroll in a vaccine trial. No association was observed between WTP and other assessed variables. Results suggest that connecting PWUD not infected with HCV to local healthcare resources may be important in motivating vaccine trial participation.


Assuntos
Ensaios Clínicos como Assunto , Acessibilidade aos Serviços de Saúde , Hepatite C/prevenção & controle , Seleção de Pacientes , Transtornos Relacionados ao Uso de Substâncias , Vacinas contra Hepatite Viral , Populações Vulneráveis/estatística & dados numéricos , Adulto , Comorbidade , Estudos Transversais , Feminino , Necessidades e Demandas de Serviços de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Marginalização Social , Abuso de Substâncias por Via Intravenosa/psicologia , Transtornos Relacionados ao Uso de Substâncias/psicologia
18.
J Behav Addict ; 7(2): 375-383, 2018 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-29788756

RESUMO

Background and aims Published research on the relationship between disordered gambling and schizophrenia is limited. However, existing data suggest that individuals with schizophrenia/schizoaffective disorder may have a high prevalence of co-occurring disordered gambling. As such, effective strategies for screening and assessing gambling-related problems in individuals with psychosis are needed. The goal of this study was to explore the correlates of increased gambling frequency and chasing behavior, a hallmark feature of gambling disorder, in a sample of individuals with schizophrenia and schizoaffective disorders. Methods Data from 336 participants who met DSM-IV criteria for schizophrenia or schizoaffective disorder were used to examine differences between non-gamblers, infrequent gamblers, frequent gamblers who do not report chasing, and frequent gamblers who report chasing on a variety of associated features and symptoms of schizophrenia and disordered gambling. Results and discussion The results of the study support the conclusion that chasing behavior in individuals with schizophrenia/schizoaffective disorder lies on a continuum of severity, with more frequent gamblers endorsing greater chasing. Chasing was also associated with indicators of lower functioning across co-occurring disorders, such as greater problems with alcohol and drugs, greater gambling involvement, and a family history of gambling problems. The findings from the study suggest the utility of screening for chasing behavior as a brief and efficient strategy for assessing risk of gambling problems in individuals with psychotic-spectrum disorders.


Assuntos
Jogo de Azar/psicologia , Transtornos Psicóticos/psicologia , Psicologia do Esquizofrênico , Idade de Início , Assistência Ambulatorial , Estudos Transversais , Feminino , Jogo de Azar/epidemiologia , Predisposição Genética para Doença , Humanos , Masculino , Pessoa de Meia-Idade , Motivação , Escalas de Graduação Psiquiátrica , Transtornos Psicóticos/epidemiologia , Transtornos Psicóticos/terapia , Fatores de Risco , Esquizofrenia/epidemiologia , Esquizofrenia/terapia , Autorrelato , Índice de Gravidade de Doença , Transtornos Relacionados ao Uso de Substâncias/epidemiologia
19.
Schizophr Res ; 171(1-3): 50-5, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26777882

RESUMO

Little research has examined the association between disordered gambling and psychosis. In addition, clinicians treating schizophrenia or schizoaffective disorders rarely screen for or treat comorbid gambling problems due to diagnostic overshadowing. Thus, the effects of disordered gambling on symptoms of schizophrenia and vice versa remain largely unexplored and unidentified in research and clinical practice. The goal of the present study was to explore qualitatively the reciprocal associations between schizophrenia/schizoaffective disorder and disordered gambling through content and functional analyses from the perspective of the affected individual. Eight participants who met DSM-IV criteria for schizophrenia or schizoaffective disorder and disordered gambling participated in a qualitative interview examining key antecedents associated with their gambling, as well as perceived functional consequences of gambling. Content analysis revealed unique patterns of responses specific to individuals with schizophrenia or schizoaffective disorder that are not typically observed in individuals with disordered gambling alone. Specifically, gambling as filling a need for activity, and gambling as a means of connecting with society/world were the notable reasons for engaging in problematic gambling. Furthermore, some, but not all participants described a direct exacerbation of their psychosis by gambling and a greater involvement in gambling due to their symptoms of schizophrenia.


Assuntos
Estudos de Avaliação como Assunto , Jogo de Azar/diagnóstico , Jogo de Azar/psicologia , Esquizofrenia/diagnóstico , Psicologia do Esquizofrênico , Adolescente , Adulto , Comorbidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Escalas de Graduação Psiquiátrica , Transtornos Psicóticos , Esquizofrenia/fisiopatologia , Adulto Jovem
20.
Psychol Addict Behav ; 29(3): 522-31, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26168224

RESUMO

The present study of recovery from cannabis use disorders was undertaken with 2 primary objectives that address gaps in the literature. The first objective was to provide an exploratory portrait of the recovery process from cannabis use disorders, comparing individuals who recovered naturally with those who were involved in treatment. The second objective was to explore systematically the similarities and differences between abstinence and moderation recoveries. Adults who have recovered from a cannabis use disorder were recruited in the community (N = 119). The abstinence and treatment-assisted participants exhibited higher levels of lifetime cannabis problem severity than the moderation and natural recovery participants, respectively. As well, cognitive factors were identified as the most useful strategies for recovery (e.g., thinking about benefits and negative consequences of cannabis), followed by behavioral factors (e.g., avoidance of triggers for use and high-risk situations). Findings lend further support to the effectiveness of cognitive, motivational, and behavioral strategies as helpful actions and maintenance factors involved in the recovery process. The findings also generally support the idea that cannabis use disorders lie on a continuum of problem severity, with moderation and natural recoveries more likely to occur at the lower end of the continuum and abstinence and treatment-assisted recoveries more likely to occur at the upper end.


Assuntos
Atitude Frente a Saúde , Cognição , Abuso de Maconha/reabilitação , Motivação , Adulto , Feminino , Humanos , Masculino , Abuso de Maconha/psicologia , Fumar Maconha/psicologia , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Adulto Jovem
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