Detalhe da pesquisa
1.
Mechanistic perspectives on anti-aminoacyl-tRNA synthetase syndrome.
Trends Biochem Sci
; 48(3): 288-302, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280495
2.
Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery.
Nucleic Acids Res
; 51(19): 10768-10781, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37739431
3.
Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase.
Nucleic Acids Res
; 51(18): 10001-10010, 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638745
4.
Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection.
Proc Natl Acad Sci U S A
; 119(48): e2212659119, 2022 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409883
5.
Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy.
Neurobiol Dis
; 195: 106501, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583640
6.
Author Correction: The selective tRNA aminoacylation mechanism based on a single Gâ¢U pair.
Nature
; 564(7736): E37, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30459470
7.
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS.
Proc Natl Acad Sci U S A
; 118(13)2021 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753480
8.
Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis.
PLoS Biol
; 18(12): e3000991, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351793
9.
X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res
; 49(17): 10106-10119, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390350
10.
New functions of aminoacyl-tRNA synthetases beyond translation.
Nat Rev Mol Cell Biol
; 11(9): 668-74, 2010 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20700144
11.
Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.
Mol Cell
; 56(2): 323-332, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284223
12.
Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation.
Nucleic Acids Res
; 48(12): 6445-6457, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32484512
13.
CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells.
Proc Natl Acad Sci U S A
; 116(39): 19440-19448, 2019 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501329
14.
Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function.
Am J Hum Genet
; 103(1): 100-114, 2018 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29979980
15.
The uniqueness of AlaRS and its human disease connections.
RNA Biol
; 18(11): 1501-1511, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33317386
16.
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.
Nature
; 526(7575): 710-4, 2015 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26503042
17.
Structural switch of lysyl-tRNA synthetase between translation and transcription.
Mol Cell
; 49(1): 30-42, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23159739
18.
Distinct ways of G:U recognition by conserved tRNA binding motifs.
Proc Natl Acad Sci U S A
; 115(29): 7527-7532, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967150
19.
Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia.
Proc Natl Acad Sci U S A
; 115(35): E8228-E8235, 2018 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30104364
20.
Neurodegenerative Charcot-Marie-Tooth disease as a case study to decipher novel functions of aminoacyl-tRNA synthetases.
J Biol Chem
; 294(14): 5321-5339, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643024