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1.
Sensors (Basel) ; 23(9)2023 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-37177586

RESUMO

Colocated multiple-input multiple-output (MIMO) radar can transmit a group of distinct waveforms via its colocated transmit antennas and the waveform diversity leads to several advantages in contrast to conventional phased-array radar. The performance depends highly on the degrees available, and element spacing can be deemed as another source of degrees of freedom. In this paper, we study the joint waveform and element spacing optimization problem. A joint waveform and array optimization criterion is proposed to match the transmit beampattern, the suppression range, and the angular sidelobes, under the constraints of minimal element spacing and total array aperture. Meanwhile, the effect of receive beamforming on suppressing mutual correlation between returns from different spatial directions is also incorporated into the optimization criterion. The optimization problem is solved by the sequential quadratic programming algorithm. Numerical results indicate that with more degrees of freedom from array spacings, colocated MIMO radar achieves a better transmit beampattern matching performance and a lower sidelobe level, compared with a fixed half-wavelength spaced array, but the benefits from additional degrees of freedom from array spacing optimization have a limit.

2.
Mol Microbiol ; 111(5): 1245-1262, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30746783

RESUMO

Ascospores are the primary inoculum in Fusarium graminearum. Interestingly, 70 of its genes have premature stop codons (PSC) and require A-to-I editing during sexual reproduction to encode full-length proteins, including the ortholog of yeast Ama1, a meiosis-specific activator of APC/C. In this study, we characterized the function of FgAMA1 and its PSC editing. FgAMA1 was specifically expressed during sexual reproduction. The Fgama1 mutant was normal in growth and perithecium formation but defective in ascospogenesis. Instead of forming four-celled, uninucleate ascospores, Fgama1 mutant produced oval, single-celled, binucleated ascospores by selfing. Some mutant ascospores began to bud and underwent additional mitosis inside asci. Expression of the wild-type or edited FgAMA1 but not the uneditable allele complemented Fgama1. In the Fgama1 x mat-1-1 outcross, over 60% of the asci had eight Fgama1 or intermediate (elongated but single-celled) ascospores, suggesting efficient meiotic silencing of unpaired FgAMA1. Deletion of FgPAL1, one of the genes upregulated in Fgama1 also resulted in defects in ascospore morphology and budding. Overall, our results showed that FgAMA1 is dispensable for meiosis but important for ascospore formation and discharge. In F. graminearum, whereas some of its targets are functional during meiosis, FgAma1 may target other proteins that function after spore delimitation.


Assuntos
Proteínas Fúngicas/genética , Fusarium/genética , Meiose , Esporos Fúngicos/crescimento & desenvolvimento , Proteínas Fúngicas/metabolismo , Fusarium/crescimento & desenvolvimento , Regulação Fúngica da Expressão Gênica , Mutação , Esporos Fúngicos/genética , Esporos Fúngicos/metabolismo , Regulação para Cima
3.
Environ Microbiol ; 22(12): 5373-5386, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33000483

RESUMO

Ascospores are the primary inoculum in Fusarium graminearum, a causal agent of wheat head blight. In a previous study, FgPAL1 was found to be upregulated in the Fgama1 mutant and important for ascosporogenesis. However, the biological function of this well-conserved gene in filamentous ascomycetes is not clear. In this study, we characterized its functions in growth, differentiation and pathogenesis. The Fgpal1 mutant had severe growth defects and often displayed abnormal hyphal tips. It was defective in infectious growth in rachis tissues and spreading in wheat heads. The Fgpal1 mutant produced conidia with fewer septa and more nuclei per compartment than the wild type. In actively growing hyphal tips, FgPal1-GFP mainly localized to the subapical collar and septa. The FgPal1 and LifeAct partially co-localized at the subapical region in an interdependent manner. The Fgpal1 mutant was normal in meiosis with eight nuclei in developing asci but most asci were aborted. Taken together, our results showed that FgPal1 plays a role in maintaining polarized tip growth and coordination between nuclear division and cytokinesis, and it is also important for infectious growth and developments of ascospores by the free cell formation process.


Assuntos
Proteínas Fúngicas/metabolismo , Fusarium/crescimento & desenvolvimento , Fusarium/patogenicidade , Divisão Celular , Proteínas Fúngicas/genética , Fusarium/genética , Hifas/genética , Hifas/crescimento & desenvolvimento , Morfogênese , Mutação , Doenças das Plantas/microbiologia , Esporos Fúngicos/genética , Esporos Fúngicos/crescimento & desenvolvimento , Esporos Fúngicos/patogenicidade , Triticum/microbiologia , Virulência
4.
J Intell ; 12(6)2024 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-38921693

RESUMO

The prevalence of media multitasking has raised concerns regarding its potential impact on cognitive abilities. Despite increasing attention given to this topic, there remains no consensus on how media multitasking is related to cognitive performance. This study aims to shed light on this issue by examining whether and how personality traits and family socioeconomic status (SES) moderate the relationship between media multitasking and reasoning performance. To this end, a large sample of university students (n = 777) completed a battery of measures, including the Raven's Advanced Progressive Matrices, the Media Multitasking Inventory, the Big Five Inventory, the Barratt Impulsiveness Scale, the Grit Scale, and the Family SES Questionnaire. Results revealed a negative correlation between media multitasking and reasoning performance. However, this relationship was substantially moderated by conscientiousness, extraversion, openness, and family SES. Specifically, media multitasking was more detrimental to reasoning performance among individuals with lower levels of conscientiousness, extraversion, openness, and family SES, whereas it was less detrimental to counterparts with higher levels of these personality traits and family SES. The proposed moderation model, for the first time, not only offers novel insights into the theoretical accounts regarding how media multitasking relates to cognitive abilities, but also identifies the protective factors that may buffer the negative impacts of media multitasking.

5.
Injury ; 55(2): 111207, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37984015

RESUMO

Calcaneal tuberosity avulsion fracture, an extra-articular injury, is a rare fracture caused internally by Achilles tendon driven following intense contraction of gastrocnemius-soleus complex, and externally by low-energy (possibly high-energy). Moreover, the risk of injuries of the skin and Achilles tendon around calcaneal tuberosity is closely related to Lee classification and Carnero-Martín de Soto Classification of calcaneal tuberosity avulsion fracture. Although the diagnosis confirmed by X-ray, digital imaging and computed tomography (CT), magnetic resonance imaging (MRI) should also be used to evaluate soft tissue. In recent years, the understanding of this fracture has witnessed the development of different internal fixation devices and surgical procedures. These advances have been further elaborated scientifically in terms of their ability to provide stable fracture reduction ad resistance to Achilles tendon forces. In order to obtain a comprehensive knowledge of the disease, this article reviewed the new understanding of the anatomy, typing, risk factors, and treatment modalities of calcaneal tuberosity avulsion fracture in recent years.


Assuntos
Calcâneo , Fratura Avulsão , Fraturas Ósseas , Humanos , Fratura Avulsão/diagnóstico por imagem , Fratura Avulsão/cirurgia , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Fraturas Ósseas/patologia , Fixação de Fratura , Calcâneo/diagnóstico por imagem , Calcâneo/cirurgia , Calcâneo/lesões , Músculo Esquelético/patologia , Fixação Interna de Fraturas
6.
Psych J ; 11(6): 895-903, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-35753077

RESUMO

The study aimed to examine the indirect factors underlying the association between work-family conflict and posttraumatic stress symptoms (PTSS) in college teachers during the COVID-19 pandemic. Three potential indirect factors were examined: perceived stress, basic psychological needs, and rumination. A total of 274 college teachers were recruited. All participants completed an electronic questionnaire that assessed their exposure to the pandemic, work-family conflict, perceived stress, basic psychological needs, rumination, and PTSS. The results showed that after controlling for pandemic exposure, gender, and age, work-family conflict was associated with PTSS via perceived stress alone, rumination alone, a path from perceived stress to basic psychological needs, and a path from perceived stress to rumination. These results indicate that work-family conflict is positively associated with PTSS indirectly via perceived stress, rumination, and basic psychological needs during the COVID-19 pandemic. These three mediators may completely explain the relation of work-family conflict to PTSS.


Assuntos
COVID-19 , Transtornos de Estresse Pós-Traumáticos , Humanos , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Transtornos de Estresse Pós-Traumáticos/psicologia , Pandemias , Conflito Familiar , Inquéritos e Questionários
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