Detalhe da pesquisa
1.
Revisiting laminin and extracellular matrix remodeling in metastatic squamous cell carcinoma: What have we learned after more than four decades of research?
Mol Carcinog
; 62(1): 5-23, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35596706
2.
Epidermal growth factor receptor signaling in precancerous keratinocytes promotes neighboring head and neck cancer squamous cell carcinoma cancer stem cell-like properties and phosphoinositide 3-kinase inhibitor insensitivity.
Mol Carcinog
; 61(7): 664-676, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35417043
3.
Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15+ Stem Cells Lead to the Development of Spontaneous Squamous Cell Carcinoma.
Int J Mol Sci
; 21(18)2020 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32916850
4.
Lessons learned from SMAD4 loss in squamous cell carcinomas.
Mol Carcinog
; 58(9): 1648-1655, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31140647
5.
mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
PLoS Genet
; 11(7): e1005291, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132202
6.
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Breast Cancer Res
; 19(1): 74, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666462
7.
Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer.
Mol Cell Proteomics
; 14(7): 1959-76, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25953087
8.
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies.
Proc Natl Acad Sci U S A
; 110(35): 14372-7, 2013 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940356
9.
Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers.
Breast Cancer Res
; 17: 148, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26637440
10.
IL-22RA2 Is a SMAD7 Target Mediating the Alleviation of Dermatitis and Psoriatic Phenotypes in Mice.
J Invest Dermatol
; 143(11): 2243-2254.e10, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37211203
11.
Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice.
J Immunother Cancer
; 11(9)2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734878
12.
Inducible nitric oxide synthase (iNOS)-activated Cxcr2 signaling in myeloid cells promotes TGFß-dependent squamous cell carcinoma lung metastasis.
Cancer Lett
; 570: 216330, 2023 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524225
13.
Therapeutic Intervention Using a Smad7-Based Tat Protein to Treat Radiation-Induced Oral Mucositis.
Int J Radiat Oncol Biol Phys
; 112(3): 759-770, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34610386
14.
Cancer-Associated Fibroblasts Facilitate Squamous Cell Carcinoma Lung Metastasis in Mice by Providing TGFß-Mediated Cancer Stem Cell Niche.
Front Cell Dev Biol
; 9: 668164, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34527666
15.
Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFß/PD-L1 blockade-treated squamous cell carcinoma.
Commun Biol
; 4(1): 1005, 2021 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433873
16.
Transforming Growth Factor-ß Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts.
Biomolecules
; 10(12)2020 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322749
17.
Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells.
Cancer Res
; 80(19): 4185-4198, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816856
18.
PARP Inhibition Enhances Radiotherapy of SMAD4-Deficient Human Head and Neck Squamous Cell Carcinomas in Experimental Models.
Clin Cancer Res
; 26(12): 3058-3070, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139402
19.
Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death.
Breast Cancer Res
; 11(6): 307, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19930622
20.
Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model.
Clin Cancer Res
; 25(2): 808-818, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185419