Detalhe da pesquisa
1.
Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores via [3+2] Cycloaddition Reaction: An MEDT Study of the Mechanism and Selectivity.
Molecules
; 28(19)2023 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37836817
2.
Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2.
Antimicrob Agents Chemother
; 66(11): e0058322, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36286539
3.
Microwave assisted Biology-Oriented Drug Synthesis (BIODS) of new N,N'-disubstituted benzylamine analogous of 4-aminoantipyrine against leishmaniasis - In vitro assay and in silico-predicted molecular interactions with key metabolic targets.
Bioorg Chem
; 120: 105621, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35074578
4.
Isolation, derivatization, in-vitro, and in-silico studies of potent butyrylcholinesterase inhibitors from Berberis parkeriana Schneid.
Bioorg Chem
; 127: 105944, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905644
5.
Synthesis, crystal structure and Hirshfeld Surface analysis of benzamide derivatives of thiourea as potent inhibitors of α-glucosidase in-vitro.
Bioorg Chem
; 107: 104531, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33339666
6.
Celebrex derivatives: Synthesis, α-glucosidase inhibition, crystal structures and molecular docking studies.
Bioorg Chem
; 106: 104499, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288319
7.
Bimetallic Iron-Palladium Catalyst System as a Lewis-Acid for the Synthesis of Novel Pharmacophores Based Indole Scaffold as Anticancer Agents.
Molecules
; 26(8)2021 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33921334
8.
Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents.
Molecules
; 26(20)2021 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684885
9.
Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity.
J Enzyme Inhib Med Chem
; 35(1): 692-701, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32156165
10.
Synthesis of a New Series of Nitrogen/Sulfur Heterocycles by Linking Four Rings: Indole; 1,2,4-Triazole; Pyridazine; and Quinoxaline.
Molecules
; 25(3)2020 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31973234
11.
Anti-Inflammatory Principles from Tamarix aphylla L.: A Bioassay-Guided Fractionation Study.
Molecules
; 25(13)2020 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32630007
12.
Catalytic asymmetric synthesis of indole derivatives as novel α-glucosidase inhibitors in vitro.
Bioorg Chem
; 79: 350-354, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29807208
13.
Synthesis of thiobarbituric acid derivatives: In vitro α-glucosidase inhibition and molecular docking studies.
Bioorg Chem
; 75: 99-105, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28926784
14.
Facile dimethyl amino group triggered cyclic sulfonamides synthesis and evaluation as alkaline phosphatase inhibitors.
Bioorg Chem
; 71: 10-18, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28139246
15.
A concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors.
Bioorg Med Chem
; 24(8): 1675-82, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26972921
16.
Synthesis of pyrimidine-2,4,6-trione derivatives: Anti-oxidant, anti-cancer, α-glucosidase, ß-glucuronidase inhibition and their molecular docking studies.
Bioorg Chem
; 68: 72-9, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27454620
17.
Ultrasonic synthesis of tyramine derivatives as novel inhibitors of α-glucosidase in vitro.
J Enzyme Inhib Med Chem
; 31(6): 1392-403, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912275
18.
Synthesis, Molecular Structure Optimization, and Cytotoxicity Assay of a Novel 2-Acetyl-3-amino-5-[(2-oxopropyl)sulfanyl]-4-cyanothiophene.
Molecules
; 21(2)2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26891285
19.
Synthesis, in vitro biological activities and in silico study of dihydropyrimidines derivatives.
Bioorg Med Chem
; 23(20): 6740-8, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26381063
20.
Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis, ß-glucuronidase inhibition activity, crystal structure, and POM analyses.
Bioorg Med Chem
; 22(23): 6715-6725, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25245672