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Nat Prod Res ; 27(11): 1023-7, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-22780302

RESUMO

The analysis of Skimmia laureola hydrodistillate by gas chromatography coupled with mass spectrometry revealed the presence of 20 constituents, representing 94.6% of the total oil. The major constituents of oil were linalyl acetate (33.0%), linalool (25.0%), limonene (8.1%), α-terpineol (5.9%) and geranyl acetate (5.9%). The monoterpene (93.4%) rich essential oil was evaluated for its antibacterial and antifungal activities against seven microorganisms by agar diffusion and microdilution methods. The oil showed appreciable antimicrobial effects against all Gram-positive bacteria tested, including methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis with MIC values 32 and 64 µg mL(-1), respectively. The oil also exhibited strong fungicidal activity against Aspergillus niger and Penicillium chrysogenum with MIC value in the range 32-16 µg mL(-1). The oil could be used in the formulation of antimicrobial agents.


Assuntos
Anti-Infecciosos/farmacologia , Óleos Voláteis/farmacologia , Folhas de Planta/química , Rutaceae/química , Anti-Infecciosos/química , Índia , Testes de Sensibilidade Microbiana , Óleos Voláteis/química
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