Detalhe da pesquisa
1.
Structural mechanism for specific binding of chemical compounds to amyloid fibrils.
Nat Chem Biol
; 19(10): 1235-1245, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37400537
2.
Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect-based chemical-enrichment method.
Proc Natl Acad Sci U S A
; 119(43): e2205255119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256816
3.
Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice.
J Neuroinflammation
; 18(1): 281, 2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861878
4.
Chemical probes for investigating protein liquid-liquid phase separation and aggregation.
Curr Opin Chem Biol
; 74: 102291, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37004350
5.
Nucleocapsid proteins from human coronaviruses possess phase separation capabilities and promote FUS pathological aggregation.
Protein Sci
; 32(12): e4826, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906538
6.
Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
iScience
; 25(1): 103701, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35036880
7.
Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation.
iScience
; 25(6): 104356, 2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35620440
8.
Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
iScience
; 25(12): 105645, 2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36505939
9.
SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation.
Protein Cell
; 13(8): 602-614, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35384603
10.
Rofecoxib Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Alleviating Cyclooxygenase-2-Mediated Mechanisms.
Front Neurosci
; 14: 817, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32903591
11.
The Molecular Mechanism of Chronic High-Dose Corticosterone-Induced Aggravation of Cognitive Impairment in APP/PS1 Transgenic Mice.
Front Mol Neurosci
; 13: 613421, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33519376
12.
Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.
Cell Res
; 32(6): 585-588, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35477998