Detalhe da pesquisa
1.
Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche.
Cell
; 150(2): 351-65, 2012 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22817897
2.
Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin.
Pharmacol Rev
; 76(1): 49-89, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37696583
3.
Epigenetic Mechanisms Contribute to Intraindividual Variations of Drug Metabolism Mediated by Cytochrome P450 Enzymes.
Drug Metab Dispos
; 51(6): 672-684, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36973001
4.
Alterations of Cytochrome P450-Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice.
Drug Metab Dispos
; 50(5): 694-703, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34348940
5.
Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
Drug Metab Dispos
; 50(5): 704-715, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34949673
6.
Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration-Approved Antisense Oligonucleotide Drugs.
Drug Metab Dispos
; 50(6): 888-897, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35221287
7.
Adverse Drug Reactions and Toxicity of the Food and Drug Administration-Approved Antisense Oligonucleotide Drugs.
Drug Metab Dispos
; 50(6): 879-887, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35221289
8.
Simultaneous Targeting of Multiple oncomiRs with Phosphorothioate or PNA-Based Anti-miRs in Lymphoma Cell Lines.
Pharm Res
; 39(11): 2709-2720, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071352
9.
The Long Noncoding RNA Hepatocyte Nuclear Factor 4α Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
Drug Metab Dispos
; 49(5): 361-368, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674270
10.
Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells.
Mol Pharmacol
; 97(4): 278-286, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029527
11.
Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis.
Drug Metab Dispos
; 48(12): 1321-1329, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077425
12.
Acetaminophen-Induced Liver Injury Alters Expression and Activities of Cytochrome P450 Enzymes in an Age-Dependent Manner in Mouse Liver.
Drug Metab Dispos
; 48(5): 326-336, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094214
13.
Fibroblast Growth Factor 15-Dependent and Bile Acid-Independent Promotion of Liver Regeneration in Mice.
Hepatology
; 68(5): 1961-1976, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29672888
14.
Enzymes and Pathways of Kavain Bioactivation and Biotransformation.
Chem Res Toxicol
; 32(7): 1335-1342, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265262
15.
Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence.
Nature
; 500(7462): 345-9, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863936
16.
A Transcriptional Regulatory Network Containing Nuclear Receptors and Long Noncoding RNAs Controls Basal and Drug-Induced Expression of Cytochrome P450s in HepaRG Cells.
Mol Pharmacol
; 94(1): 749-759, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29691280
17.
Special Section on Drug Metabolism and Precision Medicine-Editorial.
Drug Metab Dispos
; 51(3): 348-349, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36849441
18.
Special Section on Xenobiotic Receptors-Editorial.
Drug Metab Dispos
; 51(2): 205-206, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702490
19.
Special Section on Mechanism-Based Predictive Methods in Drug Discovery and Development-Editorial.
Drug Metab Dispos
; 51(9): 1064-1066, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586888
20.
Special Section on Perspectives on Drug Metabolism and Disposition, Part II-Editorial.
Drug Metab Dispos
; 51(8): 902-903, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451979