Detalhe da pesquisa
1.
Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability.
Int J Mol Sci
; 25(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38203326
2.
Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase.
Chemistry
; 25(16): 4100-4114, 2019 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30458057
3.
DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Δ9-Tetrahydrocannabinol.
Molecules
; 24(8)2019 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010235
4.
Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure.
J Pharmacol Exp Ther
; 367(2): 363-372, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30190337
5.
Irinotecan and Δ8-Tetrahydrocannabinol Interactions in Rat Liver: A Preliminary Evaluation Using Biochemical and Genotoxicity Markers.
Molecules
; 23(6)2018 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29865166
6.
A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers.
Toxicol Appl Pharmacol
; 310: 195-204, 2016 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27654152
7.
Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes.
Chem Res Toxicol
; 28(5): 1036-44, 2015 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25835984
8.
The effects of simvastatin and fenofibrate on malondialdehyde and reduced glutathione concentrations in the plasma, liver, and brain of normolipidaemic and hyperlipidaemic rats.
Arh Hig Rada Toksikol
; 74(1): 34-41, 2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014683
9.
Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease.
Chem Biol Interact
; 382: 110620, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406982
10.
Effects of concomitant use of THC and irinotecan on tumour growth and biochemical markers in a syngeneic mouse model of colon cancer.
Arh Hig Rada Toksikol
; 74(3): 198-206, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37791673
11.
4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease.
Pharmaceutics
; 14(6)2022 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745878
12.
Evaluation of Toxic Effects Induced by Sub-Acute Exposure to Low Doses of α-Cypermethrin in Adult Male Rats.
Toxics
; 10(12)2022 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36548550
13.
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.
Eur J Med Chem
; 238: 114377, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526478
14.
Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats.
Chem Biol Interact
; 338: 109287, 2021 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33129804
15.
High Doses of Δ9-Tetrahydrocannabinol Might Impair Irinotecan Chemotherapy: A Review of Potentially Harmful Interactions.
Clin Drug Investig
; 40(9): 775-787, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32696321
16.
Evaluation of oxidative stress responses and primary DNA damage in blood and brain of rats exposed to low levels of tembotrione.
Chemosphere
; 253: 126643, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32278190
17.
Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning.
ACS Chem Neurosci
; 11(7): 1072-1084, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105443
18.
Oxidative stress in triazine pesticide toxicity: a review of the main biomarker findings.
Arh Hig Rada Toksikol
; 69(2): 109-125, 2018 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29990300
19.
Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA damage in blood and brain tissue of adult male Wistar rats.
Chem Biol Interact
; 279: 51-63, 2018 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29108776
20.
Effects of the chloro-s-triazine herbicide terbuthylazine on DNA integrity in human and mouse cells.
Environ Sci Pollut Res Int
; 25(19): 19065-19081, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29721798