Detalhe da pesquisa
1.
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway.
Acta Pharmacol Sin
; 45(1): 166-179, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605050
2.
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms.
Acta Pharmacol Sin
; 43(12): 3055-3061, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050518
3.
Minor immunosuppressive spiroorthoester group-containing pregnane glycosides from the root barks of Periploca sepium.
Bioorg Chem
; 108: 104641, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517004
4.
NOD-like receptors in autoimmune diseases.
Acta Pharmacol Sin
; 42(11): 1742-1756, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33589796
5.
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling.
Acta Pharmacol Sin
; 42(4): 593-603, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747720
6.
Identification of SARS-CoV-2 entry inhibitors among already approved drugs.
Acta Pharmacol Sin
; 42(8): 1347-1353, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33116249
7.
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis.
Acta Pharmacol Sin
; 42(10): 1653-1664, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33441995
8.
(-)-Isoscopariusinâ A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis.
Angew Chem Int Ed Engl
; 60(23): 12859-12867, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620745
9.
Overview of therapeutic drug research for COVID-19 in China.
Acta Pharmacol Sin
; 41(9): 1133-1140, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32555446
10.
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients.
Acta Pharmacol Sin
; 41(9): 1167-1177, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737471
11.
[Application of active components from traditional Chinese medicine in treatment of inflammatory bowel disease].
Zhongguo Zhong Yao Za Zhi
; 44(3): 415-421, 2019 Feb.
Artigo
em Zh
| MEDLINE | ID: mdl-30989902
12.
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-α/IFN-γ-induced inflammatory response in keratinocytes and T cell-derived IL-17.
Pharmacol Res
; 129: 443-452, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29155016
13.
Spiroorthoester group-containing pregnane glycosides from the root barks of Periploca chrysantha and their inhibitory activities against the proliferation of B and T lymphocytes.
Bioorg Med Chem Lett
; 28(3): 330-333, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29292227
14.
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling.
Acta Pharmacol Sin
; 39(1): 107-116, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28880016
15.
Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages.
Acta Pharmacol Sin
; 39(10): 1633-1644, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29849131
16.
(5R)-5-hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells.
Am J Physiol Renal Physiol
; 312(4): F769-F777, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100505
17.
Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities.
J Nat Prod
; 80(4): 1102-1109, 2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28294615
18.
Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency.
Bioorg Med Chem Lett
; 26(12): 2900-2906, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27133482
19.
Eriocalyxin B ameliorates experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells.
Proc Natl Acad Sci U S A
; 110(6): 2258-63, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23345445
20.
Phainanoids A-F, a new class of potent immunosuppressive triterpenoids with an unprecedented carbon skeleton from Phyllanthus hainanensis.
J Am Chem Soc
; 137(1): 138-41, 2015 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25522036