Detalhe da pesquisa
1.
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.
Bioorg Med Chem
; 27(1): 55-64, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446439
2.
[INCREMENT]9-Tetrahydrocannabinol discriminative stimulus effects of AM2201 and related aminoalkylindole analogs in rats.
Behav Pharmacol
; 27(2-3 Spec Issue): 211-4, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26397760
3.
Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery.
Mol Pain
; 10: 27, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24742127
4.
Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201.
Eur J Pharmacol
; 960: 176168, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38059442
5.
Corrigendum: Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite.
Front Pharmacol
; 12: 630274, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33967764
6.
Design and Structure-Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors.
J Med Chem
; 64(9): 5956-5972, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900772
7.
Metabolic Profiling of a CB2 Agonist, AM9338, Using LC-MS and Microcoil-NMR: Identification of a Novel Dihydroxy Adamantyl Metabolite.
Front Pharmacol
; 11: 575691, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33101030
8.
Biochemical and Proteomic Characterization of Recombinant Human α/ß Hydrolase Domain 6.
Sci Rep
; 9(1): 890, 2019 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30696836
9.
Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats.
J Pharmacol Exp Ther
; 327(2): 584-91, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18664590
10.
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
J Med Chem
; 48(20): 6386-92, 2005 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16190764
11.
Role of the endogenous cannabinoid system in nicotine addiction: novel insights.
Front Psychiatry
; 6: 41, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25859226
12.
Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist.
Br J Pharmacol
; 142(3): 495-500, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15148260
13.
The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis.
Br J Pharmacol
; 171(2): 468-79, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24148086
14.
Differentiation between low- and high-efficacy CB1 receptor agonists using a drug discrimination protocol for rats.
Psychopharmacology (Berl)
; 231(3): 489-500, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24005529
15.
Therapeutic modulation of cannabinoid lipid signaling: metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist.
Life Sci
; 92(8-9): 482-91, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749867
16.
Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking.
PLoS One
; 7(1): e29900, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22291896
17.
AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice.
Psychopharmacology (Berl)
; 220(2): 417-26, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21989802
18.
Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia.
Brain Behav
; 2(2): 155-77, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22574283
19.
Self-medication of a cannabinoid CB2 agonist in an animal model of neuropathic pain.
Pain
; 152(9): 1976-1987, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550725
20.
Pharmacological characterization of AM1710, a putative cannabinoid CB2 agonist from the cannabilactone class: antinociception without central nervous system side-effects.
Pharmacol Biochem Behav
; 98(4): 493-502, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21382397