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1.
Int J Dent Hyg ; 21(2): 438-449, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36537784

RESUMO

OBJECTIVES: The aim of the study was to investigate patients with coronavirus disease 2019 (COVID-19) who visited dental clinics for treatment and to analyse the occurrence of additional COVID-19-confirmed cases according to the type of dental treatment and use of personal protective equipment (PPE). METHODS: Interviews were conducted in November 2021 via telephone, and written questionnaires were administered to dental hygienists working at the 24 dental clinics selected for the study, visited by patients with COVID-19. The survey focused on the visit date, the treatment received, whether or not the dental personnel wore PPE while treating the patient, and how the dental clinic and the public health centre with jurisdiction over the clinic responded after the patient's visit. RESULTS: Additional confirmed cases occurred in two of the 24 dental clinics included. In both cases, scaling was performed, dental personnel did not use a face shield, and patients with COVID-19 were asymptomatic. In 14 of the 22 dental clinics where additional confirmed cases did not occur, the dental personnel did not use face shields, and in 10 clinics, the dental personnel wore dental masks but not a KF94 mask. Based on these findings, which were obtained before the advent of the omicron variant, COVID-19 cross-infection did not appear to be high in dental clinics. CONCLUSION: The rate of COVID-19 cross-infection before the advent of the omicron variant appeared to be low in dental clinics in Korea. Therefore, patients have no reason to delay necessary dental treatment if dental personnel put effort into wearing PPE.


Assuntos
COVID-19 , Humanos , COVID-19/epidemiologia , SARS-CoV-2 , Clínicas Odontológicas , República da Coreia/epidemiologia
2.
Klin Onkol ; 31(4): 282-288, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30541311

RESUMO

BACKGROUND: Acute leukemia (AL) is a heterogeneous group of malignant hematopoietic diseases and is divided into two basic types: acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Patients with these diseases are highly immunosuppressed and therefore at a high risk of serious infections. This study aimed to perform active surveillance of enterobacteria, which cause these infections, and to determine their antibiotic resistance in patients with AL who were hospitalized at the Hemato-Oncology Center of University Hospital Olomouc. MATERIALS AND METHODS: This study involved 49 patients with AL, of whom 37 had AML (16 women and 21 men) and 12 had ALL (6 women and 6 men). The mean age of the patients was 50.5 years. Samples of clinical material were obtained over 12 months (September 2015 to August 2016) and subjected to standard microbiological examinations. Bacterial strains were identified by MALDI-TOF MS, and their antibiotic susceptibility was established by microdilution method. RESULTS: A total of 292 samples were obtained from patients with AL. Some of these samples were excluded from analysis to prevent the inclusion of identical strains from the same patient. Consequently, 146 clinical samples obtained from the following nine types of clinical materials were analyzed - throat swabs (n = 47), stools (n = 40), urine (n = 33), hemocultures (n = 11), buccal swabs (n = 5), perianal swabs (n = 4), wound swabs (n = 3), sputum (n = 2), and puncture fluid (n = 1). The most prevalent enterobacteria was Escherichia coli (n = 42), followed by Klebsiella spp. (n = 46), specifically Klebsiella pneumoniae (n = 34) and Klebsiella oxytoca (n = 12), and Enterobacter cloacae (n = 19). The most of enterobacteria were highly resistant to many tested antibiotics. CONCLUSIONS: Antibiotic-resistant enterobacteria colonize patients with hemato-oncological diseases and can cause serious infections. These antibiotic-resistant microorganisms are a serious and frequent problem. These findings together with the high level of immunosuppression mean that patients with hemato-oncological diseases are at a high risk of developing serious infections and consequently active surveillance is crucial.


Assuntos
Resistência Microbiana a Medicamentos , Infecções por Enterobacteriaceae/microbiologia , Enterobacteriaceae , Leucemia Mieloide Aguda/microbiologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/microbiologia , Antibacterianos/farmacologia , Enterobacteriaceae/efeitos dos fármacos , Enterobacteriaceae/isolamento & purificação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
3.
BMC Health Serv Res ; 17(1): 66, 2017 01 23.
Artigo em Inglês | MEDLINE | ID: mdl-28115000

RESUMO

BACKGROUND: Patients education is considered a valuable mean to prevent and control healthcare-associated infections (HAIs). This cross-sectional study aims to assess declared practices of healthcare workers (HCWs) regarding the delivery of information about HAIs to patients. METHODS: A 14-item multiple-choice questionnaire was designed to assess the attitudes and declared practices of HCWs (physicians, nurses and nursing assistants). Between October 2012 and October 2013, we surveyed a sample of HCWs from 4 acute hospitals in Piedmont (North-western Italy). Written information was available at three hospitals (A, B and C) and verbal information at the last one (hospital D). RESULTS: We surveyed 288 HCWs (79 physicians, 124 nurses and 85 healthcare assistants). At hospital A, B and C, 128 (71.6%) HCWs declared that written information was usually delivered to any patient and 145 (66.5%) that nurses usually delivered it. Only 42 (26.3%) of them - 97.6% nurses -declared that they usually delivered written information to patients. Among all surveyed HCWs, 210 (72.9%) declared that patients also receive verbal information on HAI - mainly by nurses (70.8%) and physicians (50%) - but only 88 (29,2%) - 23.8% physician and 48.8% nurses - declared that they usually informed patients. Finally, 83 (27.7%) HCWs believed that they should decide whether or not to deliver information to patient case by case. CONCLUSIONS: A formal policy requiring to deliver written information is most likely not enough to induce HCWs to better inform patients about HAIs. Health Trusts might introduce more target actions to reinforce HCWs' practices, such as training and internal auditing.


Assuntos
Atitude do Pessoal de Saúde , Infecção Hospitalar/prevenção & controle , Pessoal de Saúde/psicologia , Educação de Pacientes como Assunto , Adulto , Infecção Hospitalar/transmissão , Estudos Transversais , Feminino , França , Fidelidade a Diretrizes/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Pessoal de Saúde/estatística & dados numéricos , Política de Saúde , Hospitais , Humanos , Masculino , Pessoa de Meia-Idade , Precauções Universais , Adulto Jovem
4.
Sante Publique ; 29(1): 115-123, 2017 Mar 06.
Artigo em Francês | MEDLINE | ID: mdl-28737318

RESUMO

Objective: The implementation of a healthcare-associated infections reporting system is a principal component of infection control and quality improvement policies in healthcare institutions. This study was designed to determine the perceptions of health professionals concerning implementation of a healthcare-associated infections reporting system and to analyse factors influencing these perceptions.Methods: A descriptive cross-sectional study conducted in 2012 using a predefined, pre-tested and self-administered questionnaire in 380 health professionals working in 16 different departments of Farhat Hached University Hospital, Tunisia.Results: The majority of respondents (71.8%) reported that no healthcare-associated infections surveillance procedure had been implemented in their departments. However, most respondents (93%) recognised the value of implementation of a healthcare-associated infections reporting system in order to provide them with corrective actions (77%), to support the investigation of epidemic and emerging phenomena (49%) and to share experiences about the prevalence of healthcare-associated infections and their risk factors (44%).Conclusion: Staff training and development of a regulatory framework are essential to implementation and correct functioning of a healthcare-associated infections reporting system.


Assuntos
Atitude do Pessoal de Saúde , Infecção Hospitalar , Sistemas de Informação Hospitalar , Recursos Humanos em Hospital , Adulto , Estudos Transversais , Feminino , Hospitais Universitários , Humanos , Masculino , Pessoa de Meia-Idade , Tunísia , Adulto Jovem
5.
Sante Publique ; 29(2): 209-213, 2017 Apr 27.
Artigo em Francês | MEDLINE | ID: mdl-28737340

RESUMO

Objective: This study was designed to determine the incidence of healthcare-associated bacteraemia in intensive care units (ICU) of Ibn Rochd University Hospital, Casablanca, Morocco, the frequency of the bacterial strains isolated and their antibiotic resistance patterns. Methods: A prospective longitudinal study was conducted between May and July 2015 on patients admitted to the Ibn Rochd University Hospital ICU. The Comité technique des infections nosocomiales et des infections liées aux soins (CITNILS) definition of bacteraemia was used. Micro-organisms were isolated and identified according to standard bacteriology techniques. Antibiotic susceptibility testing was performed according to CLSI 2013 guidelines. Results: A total of 720 patients were hospitalised during the study period; 48 (6.7%) acquired healthcare-associated bacteraemia with an incidence ranging from 7.3/1,000 HD to 13.7/1,000 HD. Fifty-four bacteria were isolated: A. baumannii and K. pneumoniae each accounted for 18.5% of isolates. 66.7% of A. baumannii strains were resistant to imipenem and 20% of K. pneumoniae strains were ESBL+ Conclusion: Healthcare-associated bacteraemia raises treatment problems due to multidrug-resistant bacteria, which is why regular surveillance is necessary to evaluate the time-course of these strains and the efficacy of prevention measures.


Assuntos
Bacteriemia/epidemiologia , Infecção Hospitalar/epidemiologia , Unidades de Terapia Intensiva , Farmacorresistência Bacteriana , Feminino , Hospitais Universitários , Humanos , Incidência , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Marrocos , Estudos Prospectivos
6.
Epidemiol Infect ; 144(10): 2025-30, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-26846882

RESUMO

During outbreaks of hospital-acquired influenza-like illness (HA-ILI) healthcare workers (HCWs), patients, and visitors are each a source of infection for the other. Quantifying the effects of these various exposures will help improve prevention and control of HA-ILI outbreaks. We estimated the attributability of HA-ILI to: (1) exposure to recorded or unrecorded sources; (2) exposure to contagious patient or contagious HCW; (3) exposure during observable or unobservable contagious period of the recorded sources; and, (4) the moment of exposure. Among recorded sources, 59% [95% credible interval (CrI) 34-83] of HA-ILI of patients was associated with exposure to contagious patients and 41% (95% CrI 17-66) with exposure to contagious HCWs. Exposure during the unobservable contagiousness period of source patients accounted for 49% (95% CrI 19-75) of HA-ILI, while exposure during the unobservable contagiousness period of source HCWs accounted for 82% (95% CrI 51-99) of HA-ILI. About 80% of HA-ILIs were associated with exposure 1 day earlier. Secondary cases of HA-ILI might appear as soon as the day after the detection of a primary case highlighting the explosive nature of HA-ILI spread. Unobservable transmission was the main cause of HA-ILI transmission suggesting that symptom-based control measures alone might not prevent hospital outbreaks. The results support the rapid implementation of interventions to control influenza transmission.


Assuntos
Infecção Hospitalar/epidemiologia , Surtos de Doenças , Pessoal de Saúde , Influenza Humana/epidemiologia , Pacientes Internados , Adulto , Idoso , Idoso de 80 Anos ou mais , Infecção Hospitalar/transmissão , Feminino , França/epidemiologia , Humanos , Influenza Humana/transmissão , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Risco , Adulto Jovem
7.
Ann Intensive Care ; 14(1): 83, 2024 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-38837065

RESUMO

BACKGROUND: Immunosuppression at intensive care unit (ICU) admission has been associated with a higher incidence of ICU-acquired infections, some of them related to opportunistic pathogens. However, the association of immunosuppression with the incidence, microbiology and outcomes of ICU-acquired bacterial bloodstream infections (BSI) has not been thoroughly investigated. METHODS: Retrospective single-centered cohort study in France. All adult patients hospitalized in the ICU of Lille University-affiliated hospital for > 48 h between January 1st and December 31st, 2020, were included, regardless of their immune status. Immunosuppression was defined as active cancer or hematologic malignancy, neutropenia, hematopoietic stem cell and solid organ transplants, use of steroids or immunosuppressive drugs, human immunodeficiency virus infection and genetic immune deficiency. The primary objective was to compare the 28-day cumulative incidence of ICU-acquired bacterial BSI between immunocompromised and non-immunocompromised patients. Secondary objectives were to assess the microbiology and outcomes of ICU-acquired bacterial BSI in the two groups. RESULTS: A total of 1313 patients (66.9% males, median age 62 years) were included. Among them, 271 (20.6%) were immunocompromised at ICU admission. Severity scores at admission, the use of invasive devices and antibiotic exposure during ICU stay were comparable between groups. Both prior to and after adjustment for pre-specified baseline confounders, the 28-day cumulative incidence of ICU-acquired bacterial BSI was not statistically different between immunocompromised and non-immunocompromised patients. The distribution of bacteria was comparable between groups, with a majority of Gram-negative bacilli (~ 64.1%). The proportion of multidrug-resistant bacteria was also similar between groups. Occurrence of ICU-acquired bacterial BSI was associated with a longer ICU length-of-stay and a longer duration of invasive mechanical ventilation, with no significant association with mortality. Immune status did not modify the association between occurrence of ICU-acquired bacterial BSI and these outcomes. CONCLUSION: The 28-day cumulative incidence of ICU-acquired bacterial BSI was not statistically different between patients with and without immunosuppression at ICU admission.

8.
Emerg Med J ; 30(6): 472-5, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22761513

RESUMO

OBJECTIVE: To determine if human papillomavirus (HPV) DNA can be detected on the transvaginal sonography (TVS) probe in the emergency department (ED) and whether the current barrier method plus disinfection can prevent HPV contamination of the TVS probe. METHODS: This was a two-part cross-sectional study. In the first part, surveillance samples were taken from the TVS probe for HPV DNA detection daily for 2 months. In the second part, patients presenting with early pregnancy complications were identified in the ED and high vaginal swabs were taken for HPV DNA testing. Several probe swabs were taken to identify if contamination was possible in cases where the procedure was done on an HPV carrier. RESULTS: A total of 120 surveillance samples were obtained, nine of which (7.5%) tested positive for HPV DNA. In the second part, 76 women were recruited, of whom 14 (18.4%) were HPV carriers. After the procedure and disinfection of the probe, three out of the 14 probe samples (21%) were HPV DNA positive. CONCLUSIONS: HPV is commonly encountered in the ED and contamination of the TVS probe with HPV is possible. Although it is difficult to prove the viability and infectivity of the virus, vigilant infection control measures should be maintained.


Assuntos
Infecção Hospitalar/etiologia , Contaminação de Equipamentos , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/transmissão , Ultrassonografia/instrumentação , Adulto , Infecção Hospitalar/prevenção & controle , Estudos Transversais , DNA Viral/análise , Desinfecção/métodos , Serviço Hospitalar de Emergência , Feminino , Hong Kong , Humanos , Infecções por Papillomavirus/diagnóstico , Infecções por Papillomavirus/epidemiologia , Gravidez , Complicações Infecciosas na Gravidez/diagnóstico , Complicações Infecciosas na Gravidez/epidemiologia , Vagina/diagnóstico por imagem , Esfregaço Vaginal , Adulto Jovem
9.
Pan Afr Med J ; 45: 106, 2023.
Artigo em Francês | MEDLINE | ID: mdl-37719055

RESUMO

Introduction: in dentistry, many treatments are invasive and can lead to infections. The purpose of this study was to evaluate the prevention of healthcare-associated infections in the dental practice in Rabat. Methods: a survey on the prevention of healthcare-associated infections in Rabat dental practices was conducted among 324 practitioners. A self-administered questionnaire was used to assess their training, hygiene, protection, organization of premises, asepsis, antisepsis and use of medical devices. Data were collected using JAMOVI version 1.8.4, the χ2 and Fisher tests were used to compare the variables, the significance level was set at P<0.05. Results: only 80 subjects took part in the study. All the dentists had protective equipment, but 68 (85%) did not have instructions on what to do in case of accidental exposure to blood; 41 (62.1%) operators had qualified assistants, 36.4% had a team vaccinated against hepatitis B and 61.3% of operators and assistants had been trained to handle reusable medical devices. Seventy-six studies had isolated examination rooms, 41 had a steam steriliser and a sorting area with sharps collector. However, 35.1% had a contract for the collection of waste generated by health-care activities, posing a significant risk of infection. Conclusion: the results of this study show that most practitioners in Rabat comply with the majority of the aseptic and hygienic standards in dentistry. However, more needs to be done to ensure that staff are vaccinated.


Assuntos
Infecção Hospitalar , Hepatite B , Humanos , Infecção Hospitalar/prevenção & controle , Assepsia , Instalações de Saúde , Higiene
10.
J Clin Neurosci ; 97: 32-41, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35033779

RESUMO

The incidence of healthcare-associated respiratory tract infections in non-ventilated patients (NVA-HARTI) in neurosurgical intensive care units (ICUs) is unknown. The impact of NVA-HARTI on patient outcomes and differences between NVA-HARTI and ventilator-associated healthcare-associated respiratory tract infections (VA-HARTI) are poorly understood. Our objectives were to report the incidence, hospital length of stay (LOS), ICU LOS, and mortality in NVA-HARTI patients and compare these characteristics to VA-HARTI in neurocritical care patients. This cohort study was conducted in a neurosurgical ICU in Moscow. From 2011 to 2020, all patients with an ICU LOS > 48 h were included. A competing risk model was used for survival and risk analysis. A total of 3,937 ICU admissions were analyzed. NVA-HARTI vs VA-HARTI results were as follows: cumulative incidence 7.2 (95%CI: 6.4-8.0) vs 15.4 (95%CI: 14.2-16.5) per 100 ICU admissions; incidence rate 4.2 ± 2.0 vs 9.5 ± 3.0 per 1000 patient-days in the ICU; median LOS 32 [Q1Q3: 21, 48.5] vs 46 [Q1Q3: 28, 76.5] days; median ICU LOS 15 [Q1Q3: 10, 28.75] vs 26 [Q1Q3: 17, 43] days; mortality 12.3% (95%CI: 7.9-16.8) vs 16.7% (95%CI: 13.6-19.7). The incidence of VA-HARTI decreased over ten years while NVA-HARTI incidence did not change. VA-HARTI was an independent risk factor of death, OR 1.54 (1.11-2.14), while NVA-HARTI was not. Our findings suggest that NVA-HARTI in neurocritical care patients represents a significant healthcare burden with relatively high incidence and associated poor outcomes. Unlike VA-HARTI, the incidence of NVA-HARTI remained constant despite preventive measures. This suggests that extrapolating VA-HARTI research findings to NVA-HARTI should be avoided.


Assuntos
Infecção Hospitalar , Infecções Respiratórias , Estudos de Coortes , Infecção Hospitalar/epidemiologia , Infecção Hospitalar/terapia , Atenção à Saúde , Mortalidade Hospitalar , Humanos , Incidência , Unidades de Terapia Intensiva , Tempo de Internação , Infecções Respiratórias/epidemiologia , Infecções Respiratórias/terapia
11.
J Hosp Infect ; 127: 34-38, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35594982

RESUMO

BACKGROUND/PURPOSE: Investigation of a COVID-19 super-spreading event involving both beta and delta variants of SARS-CoV-2, following a choir in a mental health centre. METHODS: An epidemiological and biological (RT-PCR, mutations screening and sequencing) investigation was carried out to identify the chains of transmission. A morbidity and mortality review was performed using ALARM root causes analysis to understand how this superspreading event could have taken place. RESULTS: On May 25 and 26, 2021, all 13 choir participants were screened. Of these, eight were positive. None of them was vaccinated. Biological results suggested seven cases of delta variants (three confirmed by sequencing) and one case of beta variant. The screening of 141 contact individuals identified 21 subsequent cases with a suspected delta variant and two cases of suspected beta variant. Since the two index cases had similar Ct during the choir, this suggests different spreading abilities. The contributing factors were multiple, including underestimation of infectious risks by the social therapy team in relation to low individual and collective perceived vulnerability CONCLUSION: HCPs involved in sociotherapy must be aware of, and trained to mitigate, the risk of superspreading event. Conventional distancing and good natural ventilation appear to not be enough to prevent spread of more transmissible variants of SARS-CoV-2.


Assuntos
COVID-19 , COVID-19/epidemiologia , COVID-19/prevenção & controle , Hospitais Psiquiátricos , Humanos , Saúde Mental , SARS-CoV-2/genética
12.
J Pers Med ; 12(12)2022 Dec 02.
Artigo em Inglês | MEDLINE | ID: mdl-36556221

RESUMO

The World Health Organization declared the spread of the human monkeypox virus (MPXV) an "emerging threat of moderate health concern" on 23 June 2022. Although about 20,000 cases of Monkeypox (MPX) were recorded in Europe and more than 28,000 in the United States from May to October 2022, their number is still small compared to the number of dental patients treated annually. Therefore, the likelihood of oral healthcare workers encountering an MPX case is relatively low in not endemic regions. In addition, MPX-positive individuals are considered contagious only during the prodromal or acute phase. However, the exact shedding and transmission routes of MPX and the associated risk of transmission in the dental setting remain unclear. Moreover, infected subjects whose disease is confined to the head and neck may require oral and dental care because they complain of lymphadenopathy involving the cervical lymph nodes. Furthermore, MPX lesions may first appear in the oral cavity or perioral area. Therefore, given the recent spread of MPXV in non-endemic areas where dentists are not used to considering this disease in the differential diagnosis and taking appropriate preventive measures, all oral healthcare providers nowadays should be aware of the oral presentation of MPX for adequate oral screening and appropriate preventive measures for infection control in the dental practice.

13.
Viruses ; 13(10)2021 09 29.
Artigo em Inglês | MEDLINE | ID: mdl-34696389

RESUMO

South Tyrol has implemented, in 2007, a mandatory eradication program against Caprine Arthritis Encephalitis Virus (CAEV), a virus known to cause economic losses related to decreases in milk production and milk quality in goats, along with poor animal welfare and premature death. After a great initial decrease in the seroprevalence, the program has reached a tailing phase with scattered positivities. Potential risk factors associated with the multispecies farming system, a traditional approach in South Tyrol, are evaluated in this study, in order to better understand some of the potential causes leading to the tailing phenomenon. A statistically significant number of farms was selected for the present study, based on the risk factors evaluated. Even though there is no statistically significant association between the practices evaluated and the incidence of infection, the authors believe that it is important to highlight potential risks that may threaten the outcome of this eradication program.


Assuntos
Agricultura/normas , Vírus da Artrite-Encefalite Caprina/patogenicidade , Erradicação de Doenças/normas , Doenças das Cabras/epidemiologia , Infecções por Lentivirus/epidemiologia , Infecções por Lentivirus/veterinária , Agricultura/métodos , Animais , Erradicação de Doenças/métodos , Doenças das Cabras/etiologia , Cabras/virologia , Incidência , Itália/epidemiologia , Infecções por Lentivirus/etiologia , Fatores de Risco , Estudos Soroepidemiológicos
14.
Int Dent J ; 71(1): 21-26, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33616049

RESUMO

A new coronavirus (Sars-CoV-2) was detected in China at the end of 2019 and has since caused a worldwide pandemic. This virus is responsible for an acute respiratory syndrome (COVID-19), distinguished by a potentially lethal interstitial bilateral pneumonia. Because Sars-CoV-2 is highly infective through airborne contamination, the high infection risk in the dental environment is a serious problem for both professional practitioners and patients. This literature overview provides a description of the clinical aspects of COVID-19 and its transmission, while supplying valuable information regarding protection and prevention measures.


Assuntos
COVID-19 , Infecções por Coronavirus , China/epidemiologia , Odontologia , Humanos , SARS-CoV-2
15.
Biology (Basel) ; 9(3)2020 Feb 27.
Artigo em Inglês | MEDLINE | ID: mdl-32120909

RESUMO

Dental clinics, furnished with an array of specialized equipment, are commonplace, particularly in industrialized countries. Minimizing the risk of infection at the dental practice requires the formulation and implementation of strict protocols. These protocols must address the real risk posed by water contamination, particularly given that water is both integral to the function of some dental equipment, and is typically administered directly to the patient. The water in the dental clinic may be of local origin or from a water main, this can be problematic since the clinician often has little assurance regarding the quality of water reaching the dental chair. Though most modern dental equipment includes self-sterilization protocols, care must be taken that water does not stagnate anywhere in the dental equipment or clinic. The management of water quality at the dental clinic is an important part of respecting the protocols needed to manage the risk of patient infections.

16.
Pathogens ; 9(10)2020 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-32993044

RESUMO

In Europe, Puumala virus (PUUV) is responsible for nephropathia epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS). Despite the presence of its reservoir, the bank vole, on most of French territory, the geographic distribution of NE cases is heterogeneous and NE endemic and non-endemic areas have been reported. In this study we analyzed whether bank vole-PUUV interactions could partly shape these epidemiological differences. We performed crossed-experimental infections using wild bank voles from French endemic (Ardennes) and non-endemic (Loiret) areas and two French PUUV strains isolated from these areas. The serological response and dynamics of PUUV infection were compared between the four cross-infection combinations. Due to logistical constraints, this study was based on a small number of animals. Based on this experimental design, we saw a stronger serological response and presence of PUUV in excretory organs (bladder) in bank voles infected with the PUUV endemic strain. Moreover, the within-host viral diversity in excretory organs seemed to be higher than in other non-excretory organs for the NE endemic cross-infection but not for the NE non-endemic cross-infection. Despite the small number of rodents included, our results showed that genetically different PUUV strains and in a lesser extent their interaction with sympatric bank voles, could affect virus replication and diversity. This could impact PUUV excretion/transmission between rodents and to humans and in turn at least partly shape NE epidemiology in France.

17.
J Hosp Infect ; 106(3): 600-604, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32497652

RESUMO

Four patients who underwent contrast-enhanced computed tomography (CT) scanning were infected with hepatitis C virus from a contaminated multi-dose vial of NaCl. The outbreak likely occurred due to a breach in safe injection practices, resulting in contamination of the vial. Not all patients exposed to the same vial were infected. The uneven distribution of infections could be attributed to a stochastic effect of a low infectious dose. This implies that outbreak investigations need to be extended to all patients scheduled before and after the first identified infected patient to confirm or rule out nosocomial transmission.


Assuntos
Meios de Contraste/administração & dosagem , Surtos de Doenças , Hepatite C/etiologia , Injeções/efeitos adversos , Tomografia Computadorizada por Raios X/efeitos adversos , Adulto , Idoso , Idoso de 80 Anos ou mais , Infecção Hospitalar/diagnóstico , Infecção Hospitalar/etiologia , Infecção Hospitalar/virologia , Hepacivirus/genética , Hepacivirus/patogenicidade , Anticorpos Anti-Hepatite/sangue , Hepatite C/diagnóstico , Humanos , Itália , Pessoa de Meia-Idade
18.
Acta Paul. Enferm. (Online) ; 37: eAPE003511, 2024. tab
Artigo em Português | LILACS, BDENF - enfermagem (Brasil) | ID: biblio-1527578

RESUMO

Resumo Objetivo Investigar as opiniões e atitudes dos estudantes de enfermagem no papel de pacientes ou familiares de pacientes, a respeito do comportamento de higiene das mãos dos profissionais de saúde e da participação dos pacientes na campanha de higiene das mãos. Métodos Estudo transversal prospectivo realizado entre 2021-2022 no Nursing Department, Faculty of Health Sciences, de duas universidades turcas. A amostra do estudo foi composta por 330 alunos. Os dados foram coletados por meio de questionário autoaplicável. A taxa de resposta do questionário foi de 89,43%. O teste qui-quadrado foi utilizado na análise dos dados. Resultados A média de idade dos estudantes foi de 19,80±1,30 anos, 76,1% eram do sexo feminino, 50,9% afirmaram ter recebido instrução sobre Infecções Associadas aos Cuidados de Saúde (IACS). Enquanto 30,1% dos estudantes relataram realizar a higiene das mãos "9 a 11 vezes" em sua vida diária, 54,6% relataram "12 a 15 vezes" no hospital, e 96,4% dos estudantes se perguntaram se os profissionais de saúde realizavam a higiene das mãos antes de fornecer cuidados durante as internações. De acordo com 30,5% dos estudantes, lembretes dos pacientes e seus familiares sobre a realização da higiene das mãos antes do contato com os pacientes os deixariam satisfeitos. Houve diferença estatisticamente significativa entre a instrução anterior dos estudantes sobre IACS e a higiene das mãos como cuidado importante a pacientes hospitalizados (p<0,05). Conclusão Os estudantes de enfermagem apresentaram conhecimento suficiente sobre a higiene das mãos e uma atitude positiva frente aos comportamentos de higiene das mãos dos profissionais de saúde. Estudantes de enfermagem como pacientes e familiares dos pacientes podem ser incluídos nas campanhas de higiene das mãos dos profissionais de saúde, desde que as etapas do programa sejam bem planejadas.


Resumen Objetivo Investigar las opiniones y actitudes de los estudiantes de enfermería en el papel de pacientes o familiares de pacientes respecto al comportamiento de higiene de manos de los profesionales de la salud y de la participación de los pacientes en la campaña de higiene de manos. Métodos Estudio transversal prospectivo realizado entre 2021 y 2022 en el Nursing Department, Faculty of Health Sciences, de dos universidades turcas. La muestra del estudio estuvo compuesta por 330 alumnos. Los datos se recopilaron mediante cuestionario autoaplicado. El índice de respuesta del cuestionario fue de 89,43 %. Se utilizó la prueba ji cuadrado en el análisis de los datos. Resultados El promedio de edad de los estudiantes fue de 19,80±1,30 años, el 76,1 % era de sexo femenino, el 50,9 % afirmó haber recibido instrucción sobre infecciones asociadas a los cuidados de la salud (IACS). Mientras el 30,1 % de los estudiantes relató realizar la higiene de manos "9 a 11 veces" en su vida diaria, el 54,6 % relató "12 a 15 veces" en el hospital, el 96,4 % de los estudiantes se preguntó si los profesionales de la salud realizaban la higiene de manos antes de brindar cuidados durante las internaciones. El 30,5 % de los estudiantes estuvo satisfecho con los recordatorios de los pacientes y sus familiares sobre la realización de la higiene de manos antes del contacto con los pacientes. Hubo diferencia estadísticamente significativa entre la instrucción anterior de los estudiantes sobre IACS y la higiene de manos como cuidado importante en pacientes hospitalizados (p<0,05). Conclusión Los estudiantes de enfermería presentaron conocimientos suficientes sobre la higiene de manos y una actitud positiva frente a los comportamientos de higiene de manos de los profesionales de la salud. Puede incluirse a los estudiantes de enfermería como pacientes y familiares de los pacientes en las campañas de higiene de manos de los profesionales de la salud, siempre que las etapas del programa estén bien planificadas.


Abstract Objective To investigate the views and attitudes of nursing students, as patients or relatives, on healthcare professionals' hand hygiene behavior and patient participation hand hygiene campaign. Methods This prospective cross-sectional study was conducted in the nursing departments of the health and science faculties at two Turkish universities between 2021-2022. The study sample comprised 330 students. Data were collected using a self-administered questionnaire. The response rate of the questionnaire was 89.43%. Chi-square test was used in data analysis. Results The mean age of students was 19.80±1.30 years, 76.1% were female, 50.9% stated they had received education regarding healthcare-associated infections (HAI). While 30.1% of students reported they performed hand hygiene "9-11 times" in their daily lives, 54.6% reported performing "12-15 times" in the hospital, and 96.4% of students expressed wondering if healthcare professionals performed hand hygiene before offering care during hospitalizations. Among students, 30.5% stated that reminders from patients and their relatives about performing hand hygiene before contact with patients would make them happy. There was a statistically significant difference between students' previous training in HAIs and hand hygiene as an important inpatient care (p<0.05). Conclusion Nursing students had sufficient knowledge of hand hygiene and a positive attitude towards hand hygiene behaviors of healthcare professionals. Nursing students, such as patients and their relatives, can be included in hand hygiene campaigns for healthcare professionals, provided that the program steps are well planned.


Assuntos
Humanos , Masculino , Feminino , Adulto , Estudantes de Enfermagem , Controle de Infecções/métodos , Pessoal de Saúde , Higiene das Mãos , Hospitalização , Estudos Transversais , Inquéritos e Questionários
19.
J Clin Diagn Res ; 11(1): OC01-OC04, 2017 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28273989

RESUMO

INTRODUCTION: Health Care associated Infections (HAI) are the most common complications affecting the hospitalized patients. HAI are more common in developing and under developed countries. However, there are no systematic surveillance programs in these countries. AIM: To find out the burden, predisposing factors and multidrug resistant organisms causing HAI in a resource limited setting. MATERIALS AND METHODS: This prospective observational study was done at Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER). Patients aged 13 years or more with stay of more than 48 hours in a 16 bedded Medical Intensive Care Unit (MICU) between November 2011 and April 2013 were included in the study. Patients were prospectively followed up till discharge or death for the development of HAI. Device associated HAI like Ventilator Associated Pneumonia (VAP), Catheter Related-Blood Stream Infection (CR-BSI) and Catheter Associated-Urinary Tract Infections (CA-UTI) were studied. Standard laboratory methods were used for identification of microorganisms causing HAI and to test their antibiotic sensitivity. RESULTS: A total of 346 patients were included in the study with median age of 38 years. Common indications for admission to Medical Intensive Care Unit (MICU) were poisoning (31.5%); neurological illness (23.4%) like Guillian-Barre syndrome, tetanus, meningitis, encephalitis; respiratory illness (14.5%) like pneumonia, acute respiratory distress syndrome and tropical infections (7.2%) like malaria, scrub typhus, leptospirosis. Fifty percent (174/346) patients developed one or more HAI with VAP being the most common. The rates of HAI per 1000 device days for VAP, CR-BSI, CA-UTI were 72.56, 3.98 and 12.4, respectively. Acinetobacter baumannii was the most common organism associated with HAI. Multidrug resistance was seen in 74% of the isolates. CONCLUSION: The burden of HAI, especially with MDR organisms, in resource constrained setting like ours is alarming. There is urgent need for infection control and monitoring system to reduce HAI.

20.
Rev Med Inst Mex Seguro Soc ; 55(Suppl 4): S350-S356, 2017.
Artigo em Espanhol | MEDLINE | ID: mdl-29791791

RESUMO

Background: Infections associated with health care, previously known as nosocomial infections, constitute one of the main causes of morbidity and mortality in hospital. The aim of this study is to estimate the lethality of HAI, as well as the risk of dying from HAI versus mortality by other causes. Methods: We analyzed the historical cohort of IAAS of the Epidemiology service of a tertiary-level hospital, from 2012 to 2017. The incidence analysis and the probability of death of IAAS were made against other causes, as well as the analysis of age, period-cohort of lethality of IAAS. Results: The incidence of IAAS ranged from 27.9 to 31.5 IAAS/1000 person-days between 2012 and 2017, the probability of having an IAAS in ICU is 3.51 (CI95%: 2.93-4.20), p < 0.01, NAVM lethality against any other causes of death had a relative risk (RR) of 6.06 (CI95%: 2.91-12.6) in 2016, RR was 4.01 (CI95%: 1.59-10.09) in ITUAC in 2015, no effect of age, cohort or period in the case of IAAS was identified. Conclusions: IAAS remain to be an important public health problem in our country, without excluding our medical unit, it is important to redirect efforts to reduce them in the medium term.


Introducción: Las infecciones asociadas a la atención a la salud, anteriormente conocidas como nosocomiales, constituyen una de las principales causas de morbimortalidad hospitalaria. El objetivo de este trabajo fue estimar el riesgo de fallecer de aquellos pacientes hospitalizados en una Unidad Médica de Alta Especialidad (UMAE) cuando se asocian a infecciones asociadas a la atención en salud (IAAS) más frecuente en nuestro medio. Métodos: Se realizó un análisis de una cohorte histórica de IAAS por la División de Epidemiología de la UMAE, del 2012 al 2017. Se estimó la incidencia y la probabilidad de muerte por IAAS y se comparó con otras causas, analizando las variables de edad, cohorte y periodo de la letalidad. Resultados: La incidencia de IAAS entre 2012 y 2017 fue de 27.9 a 31.5 IAAS/1000 días estancia, la probabilidad de tener una IAAS al estar en la Unidad de Cuidados Intensivos fue de 3.51 (IC95%: 2.93-4.20) p < 0.01, la letalidad por neumonía asociada a ventilación mecánica frente a otras causas en 2016 tuvo un riesgo relativo (RR) de 6.06 (IC95%: 2.91-12.6), y para infección del tracto urinario asociado a cateter el RR fue de 4.01 (IC95%: 1.59-10.09). Conclusiones: Las IAAS siguen siendo un importante problema de salud pública en nuestro medio; es importante redirigir los esfuerzos para abatir las IAAS en el mediano y corto plazo


Assuntos
Infecção Hospitalar/mortalidade , Mortalidade Hospitalar , Centros de Atenção Terciária , Humanos , Incidência , México/epidemiologia , Fatores de Risco
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