A comparison of computer adaptive tests (CATs) and short forms in terms of accuracy and number of items administrated using PROMIS profile.

PURPOSE: In the Patient-Reported Outcomes Measurement Information System (PROMIS), seven domains (Physical Function, Anxiety, Depression, Fatigue, Sleep Disturbance, Social Function, and Pain Interference) are packaged together as profiles. Each of these domains can also be assessed using computer adaptive tests (CATs) or short forms (SFs) of varying length (e.g., 4, 6, and 8 items). We compared the accuracy and number of items administrated of CAT versus each SF. METHODS: PROMIS instruments are scored using item response theory (IRT) with graded response model and reported as T scores (mean = 50, SD = 10). We simulated 10,000 subjects from the normal distribution with mean 60 for symptom scales and 40 for function scales, and standard deviation 10 in each domain. We considered a subject's score to be accurate when the standard error (SE) was less than 3.0. We recorded range of accurate scores (accurate range) and the number of items administrated. RESULTS: The average number of items administrated in CAT was 4.7 across all domains. The accurate range was wider for CAT compared to all SFs in each domain. CAT was notably better at extending the accurate range into very poor health for Fatigue, Physical Function, and Pain Interference. Most SFs provided reasonably wide accurate range. CONCLUSIONS: Relative to SFs, CATs provided the widest accurate range, with slightly more items than SF4 and less than SF6 and SF8. Most SFs, especially longer ones, provided reasonably wide accurate range.

The effect of scanning distance on the accuracy of intra-oral scanners used in dentistry.

The aim of this study was to evaluate the factors affecting intra-oral scanner accuracy by analyzing variation in measurements of a dental model according to scanning distance. A dental cast, including a prepared left mandibular first molar, was used. Rectangular frames measuring 20 × 30 mm with heights of 2.5, 5.0, and 7.5 mm were made. The model was scanned 10 times with a reference scanner to obtain the true value. Scanning was performed 10 times at four distances of 0, 2.5, 5.0, and 7.5 mm with the frame of each height using the following intra-oral scanners: TRIOS; CS 3500; and PlanScan. In the linear distance measurement method (2D), measurements were taken at five parameters using the Rapidform software. In the best-fit alignment method (3D), using the Geomagic Control X, the root mean square values of the two scan images were calculated. In the 2D comparison, the different from the reference value was the smallest at 2.5 and 5.0 mm. In the 3D comparison, 2.5 and 5.0 mm were the most accurate, and 0 mm was the least accurate among the four distances. To the best of our knowledge, this study was the first to evaluate the accuracy of scanning distances, and found a difference between the accuracy of the scanning distance and the accuracy of the scanner. Moreover, the results of this study indicated that the scanning distance was a variable affecting accuracy. Clin. Anat. 32:430-438, 2019. © 2019 Wiley Periodicals, Inc.

Complete-arch accuracy of intraoral scanners.

STATEMENT OF PROBLEM: Intraoral scanners have shown varied results in complete-arch applications. PURPOSE: The purpose of this in vitro study was to evaluate the complete-arch accuracy of 4 intraoral scanners based on trueness and precision measurements compared with a known reference (trueness) and with each other (precision). MATERIAL AND METHODS: Four intraoral scanners were evaluated: CEREC Bluecam, CEREC Omnicam, TRIOS Color, and Carestream CS 3500. A complete-arch reference cast was created and printed using a 3-dimensional dental cast printer with photopolymer resin. The reference cast was digitized using a laboratory-based white light 3-dimensional scanner. The printed reference cast was scanned 10 times with each intraoral scanner. The digital standard tessellation language (STL) files from each scanner were then registered to the reference file and compared with differences in trueness and precision using a 3-dimensional modeling software. Additionally, scanning time was recorded for each scan performed. The Wilcoxon signed rank, Kruskal-Wallis, and Dunn tests were used to detect differences for trueness, precision, and scanning time (α=.05). RESULTS: Carestream CS 3500 had the lowest overall trueness and precision compared with Bluecam and TRIOS Color. The fourth scanner, Omnicam, had intermediate trueness and precision. All of the scanners tended to underestimate the size of the reference file, with exception of the Carestream CS 3500, which was more variable. Based on visual inspection of the color rendering of signed differences, the greatest amount of error tended to be in the posterior aspects of the arch, with local errors exceeding 100 µm for all scans. The single capture scanner Carestream CS 3500 had the overall longest scan times and was significantly slower than the continuous capture scanners TRIOS Color and Omnicam. CONCLUSIONS: Significant differences in both trueness and precision were found among the scanners. Scan times of the continuous capture scanners were faster than the single capture scanners.

Accuracy and reproducibility of virtual edentulous casts created by laboratory impression scan protocols.

STATEMENT OF PROBLEM: Although computer-aided design and computer-aided manufacturing (CAD-CAM) complete removable dental prostheses (CRDPs) have gained popularity, conventional impressions are still common for CAD-CAM CRDP treatment. These need to be digitized and converted into virtual edentulous casts with a laboratory impression scan protocol during prosthesis fabrication. How this can best be accomplished is unclear. PURPOSE: The purpose of this in vitro study was to compare the accuracy and reproducibility of virtual edentulous casts created by a dental laboratory laser scanner and a cone beam computed tomography (CBCT) scanner with a digitized master cast. MATERIAL AND METHODS: A master cast was digitized as the virtual reference cast. Ten polyvinyl siloxane impressions were made on the master cast and scanned with the dental laboratory laser scanner and CBCT scanner. The impressions were sprayed with antiglare spray and rescanned. Four groups of virtual study casts (N=40) were created from the impression scans. All virtual study casts and the reference cast were registered with surface-matching software, and the root mean square (RMS) values (representation of overall accuracy) and percentage of measurement data points within 1 standard deviation (SD) of mean RMS values (%, representation of overall reproducibility) among the 4 study groups were measured. Additionally, 95 numeric distance differences (representation of accuracy at each region) were measured in 5 distinct regions: the apex of the denture border, 6 mm from denture border, crest of the ridge, palate, and posterior palatal seal. The repeated-measures ANOVA and post hoc test (t grouping) were used to determine statistical differences (α=.05). RESULTS: The laboratory scanner group had a significantly larger RMS value (4.0 ±0.3 µm, P<.001) and smaller percentage of measurement data points within 1 SD of mean RMS value (77.5 ±1.0%, P<.001). The RMS values between the CBCT scanner (1.2 ±0.3 µm) and CBCT scanner-spray (1.1 ±0.2 µm) groups were not significantly different (P=.968), and the percentage of measurement data points within 1 SD of mean RMS values (90.1 ±1.1% versus 89.5 ±0.8%) were also not significantly different (P=.662). The numeric distance differences across 5 regions were affected by the scanning protocols (P<.001). The laboratory scanner and laboratory scanner-spray groups had significantly higher numeric distance differences at the apex of the denture border and crest of the ridge regions (P<.001). CONCLUSIONS: The CBCT scanner created more accurate and reproducible virtual edentulous casts, and the antiglare spray only significantly improved the accuracy and reproducibility of virtual edentulous casts created by the dental laboratory laser scanner. The accuracy of the virtual edentulous casts was different across 5 regions and was affected by the scanning protocols.

Digital evaluation of absolute marginal discrepancy: A comparison of ceramic crowns fabricated with conventional and digital techniques.

STATEMENT OF PROBLEM: Marginal discrepancy is key to evaluating the accuracy of fixed dental prostheses. An improved method of evaluating marginal discrepancy is needed. PURPOSE: The purpose of this in vitro study was to evaluate the absolute marginal discrepancy of ceramic crowns fabricated using conventional and digital methods with a digital method for the quantitative evaluation of absolute marginal discrepancy. The novel method was based on 3-dimensional scanning, iterative closest point registration techniques, and reverse engineering theory. MATERIAL AND METHODS: Six standard tooth preparations for the right maxillary central incisor, right maxillary second premolar, right maxillary second molar, left mandibular lateral incisor, left mandibular first premolar, and left mandibular first molar were selected. Ten conventional ceramic crowns and 10 CEREC crowns were fabricated for each tooth preparation. A dental cast scanner was used to obtain 3-dimensional data of the preparations and ceramic crowns, and the data were compared with the "virtual seating" iterative closest point technique. Reverse engineering software used edge sharpening and other functional modules to extract the margins of the preparations and crowns. Finally, quantitative evaluation of the absolute marginal discrepancy of the ceramic crowns was obtained from the 2-dimensional cross-sectional straight-line distance between points on the margin of the ceramic crowns and the standard preparations based on the circumferential function module along the long axis. RESULTS: The absolute marginal discrepancy of the ceramic crowns fabricated using conventional methods was 115 ±15.2 µm, and 110 ±14.3 µm for those fabricated using the digital technique was. ANOVA showed no statistical difference between the 2 methods or among ceramic crowns for different teeth (P>.05). CONCLUSIONS: The digital quantitative evaluation method for the absolute marginal discrepancy of ceramic crowns was established. The evaluations determined that the absolute marginal discrepancies were within a clinically acceptable range. This method is acceptable for the digital evaluation of the accuracy of complete crowns.

Clinical complications and quality assessments with computer-engineered complete dentures: A systematic review.

STATEMENT OF PROBLEM: Computer-engineered complete dentures (CECDs) have significant potential as shown by recent reports of outcomes and specific applications. An understanding of complications and quality assessment factors associated with CECDs from compiled data is lacking in published reports. PURPOSE: The purpose of this systematic review was to determine the clinical complications and quality assessments related to CECDs. MATERIAL AND METHODS: Electronic searches of publications in English from January 1984 to September 2016 were performed in MEDLINE and Cochrane databases, with the results enriched by manual searches and citation mining to address 2 population intervention comparison outcome (PICO) questions: what are the clinical complications associated with CECDs, and what are the quality assessments with CECDs? RESULTS: A review of 5 selected articles (limited data) on CECDs revealed patient dissatisfaction related to overall outcome (25.49%), inadequate retention (20.73%), and esthetic concerns (15.09%) as common complications. Quality assessment factors that were used to report complications were identified. CONCLUSIONS: Patient dissatisfaction, inadequate retention, and inadequate esthetics were the most common complications with CECDs. The addition of a trial placement option for CECDs could result in a better clinical outcome, reducing the incidence of other complications related to occlusal vertical dimension, centric relationship, tooth arrangement, and esthetics, improving patient satisfaction, and reducing remakes. The difficulty in reading the digital preview for an objective assessment before fabrication is a unique but not a common, complication for CECDs.

Principles and Benefits of Explicitly Designed Medical Device Safety Architecture.

The complexity of medical devices and the processes by which they are developed pose considerable challenges to producing safe designs and regulatory submissions that are amenable to effective reviews. Designing an appropriate and clearly documented architecture can be an important step in addressing this complexity. Best practices in medical device design embrace the notion of a safety architecture organized around distinct operation and safety requirements. By explicitly separating many safety-related monitoring and mitigation functions from operational functionality, the aspects of a device most critical to safety can be localized into a smaller and simpler safety subsystem, thereby enabling easier verification and more effective reviews of claims that causes of hazardous situations are detected and handled properly. This article defines medical device safety architecture, describes its purpose and philosophy, and provides an example. Although many of the presented concepts may be familiar to those with experience in realization of safety-critical systems, this article aims to distill the essence of the approach and provide practical guidance that can potentially improve the quality of device designs and regulatory submissions.

Computer-aided design of dry powder inhalers using computational fluid dynamics to assess performance.

Dry powder inhalers (DPIs) are gaining popularity for the delivery of drugs. A cost effective and efficient delivery device is necessary. Developing new DPIs by modifying an existing device may be the simplest way to improve the performance of the devices. The aim of this research was to produce a new DPIs using computational fluid dynamics (CFD). The new DPIs took advantages of the Cyclohaler® and the Rotahaler®. We chose a combination of the capsule chamber of the Cyclohaler® and the mouthpiece and grid of the Rotahaler®. Computer-aided design models of the devices were created and evaluated using CFD. Prototype models were created and tested with the DPI dispersion experiments. The proposed model 3 device had a high turbulence with a good degree of deagglomeration in the CFD and the experiment data. The %fine particle fraction (FPF) was around 50% at 60 L/min. The mass median aerodynamic diameter was around 2.8-4 µm. The FPF were strongly correlated to the CFD-predicted turbulence and the mechanical impaction parameters. The drug retention in the capsule was only 5-7%. In summary, a simple modification of the Cyclohaler® and Rotahaler® could produce a better performing inhaler using the CFD-assisted design.

Die spacer thickness reproduction for central incisor crown fabrication with combined computer-aided design and 3D printing technology: an in vitro study.

STATEMENT OF PROBLEM: The inability to control die spacer thickness has been reported. However, little information is available on the congruency between the computer-aided design parameters for die spacer thickness and the actual printout. PURPOSE: The purpose of this study was to evaluate the accuracy and precision of the die spacer thickness achieved by combining computer-aided design and 3-dimensional printing technology. MATERIAL AND METHODS: An ivorine maxillary central incisor was prepared for a ceramic crown. The prepared tooth was duplicated by using polyvinyl siloxane duplicating silicone, and 80 die-stone models were produced from Type IV dental stone. The dies were randomly divided into 5 groups with assigned die spacer thicknesses of 25 µm, 45 µm, 65 µm, 85 µm, and 105 µm (n=16). The printed resin copings, obtained from a printer (ProJet DP 3000; 3D Systems), were cemented onto their respective die-stone models with self-adhesive resin cement and stored at room temperature until sectioning into halves in a buccolingual direction. The internal gap was measured at 5 defined locations per side of the sectioned die. Images of the printed resin coping/die-stone model internal gap dimensions were obtained with an inverted bright field metallurgical microscope at ×100 magnification. The acquired digital image was calibrated, and measurements were made using image analysis software. Mixed models (α=.05) were used to evaluate accuracy. A false discovery rate at 5% was used to adjust for multiple testing. Coefficient of variation was used to determine the precision for each group and was evaluated statistically with the Wald test (α=.05). RESULTS: The accuracy, expressed in terms of the mean differences between the prescribed die spacer thickness and the measured internal gap (standard deviation), was 50 µm (11) for the 25 µm group simulated die spacer thickness, 30 µm (10) for the 45 µm group, 15 µm (14) for the 65 µm group, 3 µm (23) for the 85 µm group, and -10 µm (32) for the 105 µm group. The precision mean of the measurements, expressed as a coefficient of variation, ranged between 14% and 33% for the 5 groups. CONCLUSIONS: For the accuracy evaluation, statistically significant differences were found for all the groups, except the group of 85 µm. For the precision assessment, the coefficient of variation was above 10% for all groups, showing the printer's inability to reproduce the uniform internal gap within the same group.

Influence of standardization on the precision (reproducibility) of dental cast analysis with virtual 3-dimensional models.

INTRODUCTION: Virtual 3-dimensional (3D) models obtained by scanning of physical casts have become an alternative to conventional dental cast analysis in orthodontic treatment. If the precision (reproducibility) of virtual 3D model analysis can be further improved, digital orthodontics could be even more widely accepted. The purpose of this study was to clarify the influence of "standardization" of the target points for dental cast analysis using virtual 3D models. Physical plaster models were also measured to obtain additional information. METHODS: Five sets of dental casts were used. The dental casts were scanned with R700 (3Shape, Copenhagen, Denmark) and REXCAN DS2 3D (Solutionix, Seoul, Korea) scanners. In this study, 3 system and software packages were used: SureSmile (OraMetrix, Richardson, Tex), Rapidform (Inus, Seoul, Korea), and I-DEAS (SDRC, Milford, Conn). RESULTS: Without standardization, the maximum differences were observed between the SureSmile software and the Rapidform software (0.39 mm ± 0.07). With standardization, the maximum differences were observed between the SureSmile software and measurements with a digital caliper (0.099 mm ± 0.01), and this difference was significantly greater (P <0.05) than the 2 other mean difference values. Furthermore, the results of this study showed that the mean differences "WITH" standardization were significantly lower than those "WITHOUT" standardization for all systems, software packages, or methods. CONCLUSIONS: The results showed that elimination of the influence of usability or habituation is important for improving the reproducibility of dental cast analysis.

Understanding dental CAD/CAM for restorations--accuracy from a mechanical engineering viewpoint.

As is the case in the field of medicine, as well as in most areas of daily life, digital technology is increasingly being introduced into dental practice. Computer-aided design/ computer-aided manufacturing (CAD/CAM) solutions are available not only for chairside practice but also for creating inlays, crowns, fixed partial dentures (FPDs), implant abutments, and other dental prostheses. CAD/CAM dental practice can be considered as the handling of devices and software processing for the almost automatic design and creation of dental restorations. However, dentists who want to use dental CAD/CAM systems often do not have enough information to understand the variations offered by such technology practice. Knowledge of the random and systematic errors in accuracy with CAD/CAM systems can help to achieve successful restorations with this technology, and help with the purchasing of a CAD/CAM system that meets the clinical needs of restoration. This article provides a mechanical engineering viewpoint of the accuracy of CAD/ CAM systems, to help dentists understand the impact of this technology on restoration accuracy.

A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing.

BACKGROUND: Canadian Blood Services has been conducting quality monitoring of red blood cell (RBC) components since 2005, a period spanning the implementation of semiautomated component production. The aim was to compare the quality of RBC components produced before and after this production method change. STUDY DESIGN AND METHODS: Data from 572 RBC units were analyzed, categorized by production method: Method 1, RBC units produced by manual production methods; Method 2, RBC units produced by semiautomated production and the buffy coat method; and Method 3, RBC units produced by semiautomated production and the whole blood filtration method. RBC units were assessed using an extensive panel of in vitro tests, encompassing regulated quality control criteria such as hematocrit (Hct), hemolysis, and hemoglobin (Hb) levels, as well as adenosine triphosphate, 2,3-diphosphoglycerate, extracellular K(+) and Na(+) levels, methemoglobin, p50, RBC indices, and morphology. RESULTS: Throughout the study, all RBC units met mandated Canadian Standards Association guidelines for Hb and Hct, and most (>99%) met hemolysis requirements. However, there were significant differences among RBC units produced using different methods. Hb content was significantly lower in RBC units produced by Method 2 (51.5 ± 5.6 g/unit; p < 0.001). At expiry, hemolysis was lowest in Method 2-produced RBC units (p < 0.05) and extracellular K(+) levels were lowest in units produced by Method 1 (p < 0.001). CONCLUSION: While overall quality was similar before and after the production method change, the observed differences, although small, indicate a lack of equivalency across RBC products manufactured by different methods.

Assessing the accuracy of computer color matching with a new dental porcelain shade system.

STATEMENT OF PROBLEM: In a previous study, a novel computer color matching system for dental ceramic restoration was developed, and 21 new shades were established. Theoretically, a natural tooth color can be accurately reproduced by combining 2 or 3 ceramic mixtures from the database of 21 new shades. PURPOSE: The purpose of this study was to test the use of these shades in conjunction with the computer color matching system to determine their ability to accurately reproduce the body color of 29 shade tabs from a shade guide (VITAPAN 3D-Master). MATERIAL AND METHODS: Disks of 21 reference shades were prepared with porcelain (Cerabien CZR) and polished to 1.0 mm thickness. A spectrophotometer was used to measure the reflectance values from 380 to 780 nm for each disk; the scattering coefficient and absorption coefficient were determined. By using the reflectance values and the scattering and absorption coefficients, the computer color matching program generated porcelain prescriptions incorporating proportions from the 21 reference shades to reproduce the shade tabs. Disks were fabricated from the prescriptions, polished to 1.0 mm thickness, then placed over a zirconia core plate and measured with the spectrophotometer. The color differences (ΔE*) between the shade tabs and the corresponding ceramic disks were calculated. Statistical analysis was performed with the 1-sample t test. RESULTS: The ΔE* values between computer color matching specimens and the target shade tabs varied from 0.5 to 1.9, with an average ΔE* of 1.3, which was significantly less than the clinically detectable ΔE* threshold of 1.6 (P<.001). CONCLUSIONS: The computer color matching system with the established 21 new shades is accurate and effective for reproducing tooth shades.

Scanning accuracy and precision in 4 intraoral scanners: an in vitro comparison based on 3-dimensional analysis.

STATEMENT OF PROBLEM: Intraoral scanners may use proprietary acquisition and manufacturing processes. However, limited information is available regarding their accuracy, their precision, and the influence that refraction or coating may have on their output. PURPOSE: The purpose of the study was to evaluate the scanning accuracy and precision of 4 intraoral scanners and to assess the influence of different test materials and coating thicknesses. MATERIAL AND METHODS: Models were fabricated in 3 materials (polymethyl methacrylate [Telio CAD], titanium, and zirconia) and reference scanned with an industrial optical scanner. The models were scanned with intraoral scanners (3M Lava COS, Cerec AC/Bluecam, E4D, and iTero). A thick layer of coating was applied and scanned (3M Lava COS). Further evaluation on a gypsum cast was undertaken for the E4D system. Data were evaluated by using 3-dimensional analysis with "3D compare" software commands (3D compare analysis) regarding standard, mean, and maximum deviations, with subsequent statistical analysis. RESULTS: The 3M Lava COS, Cerec AC/Bluecam, and iTero generally displayed similar results regarding deviations. Maximum deviations, however, increased by several factors for the noncoating scanners (iTero and E4D). Statistical significance was found regarding material properties for noncoating scanners (P<.05). iTero displayed consistent material-specific, localized errors on the translucent material (Telio CAD). E4D showed the largest deviations. Scans of the gypsum cast displayed specific localized areas with greater deviations. Excessive coating was nonsignificant. CONCLUSIONS: Significant differences were found between the coating and noncoating scanners, and specific scanning errors for the system with parallel confocal microscopy were found for certain model materials. Specific areas of sizable deviations for the system with laser triangulation technology can be explained by the scanner design and noncoating technology. Excessive coating had no negative effect.

Clinical use of a direct chairside oral scanner: an assessment of accuracy, time, and patient acceptance.

INTRODUCTION: Chairside oral scanners allow direct digital acquisition of the intraoral situation and can eliminate the need for conventional impressions. In this study, we aimed to assess accuracy, scan time, and patient acceptance of a chairside oral scanner when used for full-arch scans; these are critical factors for acceptance of this technology in the orthodontic setting. METHODS: Fifteen patients had digital models made from both intraoral scans (Lava COS; 3M ESPE, St Paul, Minn) and alginate impressions. Each procedure was timed, and patient preference was assessed with a survey. In addition, digital models were made from 5 plaster model pairs using the intraoral scanner and an orthodontic model scanner. Model pairs were digitally superimposed, and differences between models were quantified. Accuracy was assessed using the Bland-Altman method. Time differences were tested for statistical significance with the Student t test. RESULTS: Digital models made using the chairside oral scanner and either impressions or the orthodontic model scanner did not differ significantly. The chair time required to take impressions was significantly shorter than the time required for the intraoral scans. When processing time was included, the time requirement did not differ significantly between methods. Although 73.3% of the patients preferred impressions because they were "easier" or "faster," 26.7% preferred the scan because it was "more comfortable." CONCLUSIONS: Despite the high accuracy of chairside oral scanners, alginate impressions are still the preferred model acquisition method with respect to chair time and patient acceptance. As digital technology continues to progress, intraoral scanning may become more accepted for use in orthodontics.

Accuracy of chairside-milled CAD/CAM drill guides for dental implants.

PURPOSE: To describe a chairside method for producing implant guides based solely on digital data and present a first assessment of in vitro accuracy on plaster models. MATERIAL AND METHODS: Twenty-four implants were planned and pilot drillings were performed according to a new protocol, which is based on the registration of CBCT and CAD/CAM data. Chairside-milled one-piece drill guides were used to transfer the virtual plan into reality. Accuracy measurements were acquired. RESULTS: Chairside-milled drill guides were successfully fabricated and accuracy for pilot drillings was between 0.17 and 1.3 mm. CONCLUSION: Within the limits of this experimental study, chairside-milled drill guides are feasible and do not require any preparation before CBCT scanning.

Accuracy of ceramic restorations made with two CAD/CAM systems.

STATEMENT OF PROBLEM: Different types of CAD/CAM systems are currently available, but information regarding which system produces the best marginal fit is lacking. PURPOSE: The purpose of this study was to evaluate the effect of 2 different CAD/CAM systems (Cerec inLab, Kavo Everest) on the marginal fit of 2 types of zirconia-based and lithium disilicate crowns. MATERIAL AND METHODS: Forty zirconia-based and lithium disilicate crowns, 20 each, were fabricated with the Cerec inLab and Everest CAD/CAM systems on a specially designed stainless steel die to ensure the standardization of specimen shape and dimensions. The vertical marginal fit for all tested crowns was evaluated by using a digital microscope at ×100 magnification, and the data were tabulated and statistically analyzed with 2-way ANOVA, followed by the Tukey honestly significant difference (HSD) test with a confidence level of .05 to determine the mean differences. RESULTS: The results showed that the CAD/CAM technique, ceramic type, and their interaction had a statistically significant effect on the mean marginal fit of both ceramic types tested. CONCLUSIONS: Better marginal fit values were exhibited by the Everest CAD/CAM technique for both ceramic types tested.

Accuracy of complete-arch dental impressions: a new method of measuring trueness and precision.

STATEMENT OF PROBLEM: A new approach to both 3-dimensional (3D) trueness and precision is necessary to assess the accuracy of intraoral digital impressions and compare them to conventionally acquired impressions. PURPOSE: The purpose of this in vitro study was to evaluate whether a new reference scanner is capable of measuring conventional and digital intraoral complete-arch impressions for 3D accuracy. MATERIAL AND METHODS: A steel reference dentate model was fabricated and measured with a reference scanner (digital reference model). Conventional impressions were made from the reference model, poured with Type IV dental stone, scanned with the reference scanner, and exported as digital models. Additionally, digital impressions of the reference model were made and the digital models were exported. Precision was measured by superimposing the digital models within each group. Superimposing the digital models on the digital reference model assessed the trueness of each impression method. Statistical significance was assessed with an independent sample t test (α=.05). RESULTS: The reference scanner delivered high accuracy over the entire dental arch with a precision of 1.6 ±0.6 µm and a trueness of 5.3 ±1.1 µm. Conventional impressions showed significantly higher precision (12.5 ±2.5 µm) and trueness values (20.4 ±2.2 µm) with small deviations in the second molar region (P<.001). Digital impressions were significantly less accurate with a precision of 32.4 ±9.6 µm and a trueness of 58.6 ±15.8µm (P<.001). More systematic deviations of the digital models were visible across the entire dental arch. CONCLUSIONS: The new reference scanner is capable of measuring the precision and trueness of both digital and conventional complete-arch impressions. The digital impression is less accurate and shows a different pattern of deviation than the conventional impression.

Comparison of manually shaped and computer-shaped titanium mesh for repairing large frontotemporoparietal skull defects after traumatic brain injury.

OBJECT: The object of this study was to compare the effects and complications of manual and computer-aided shaping of titanium meshes for repairing large frontotemporoparietal skull defects following traumatic brain injury. METHODS: From March 2005 to June 2011, 161 patients with frontotemporoparietal skull defects were observed. Patients were divided into 2 groups according to the repair materials used for cranioplasty: 83 cases used computer-aided shaping for the titanium mesh, whereas the remaining 78 cases used a manually shaped titanium mesh. The advantages and disadvantages of the 2 methods were compared. RESULTS: No case of titanium mesh loosening occurred in either group. Subcutaneous fluid collection, titanium mesh tilt, and temporal muscle pain were the most common complications. In the manually shaped group, there were 14 cases of effusion, 10 cases of titanium mesh tilt, and 15 cases of temporal muscle pain. In the computer-aided group, there were 6 cases of effusion, 3 cases of titanium mesh tilt, and 6 cases of temporal muscle pain. The differences were significant between the 2 groups (p < 0.05). Other common complications were scalp infection, exposure of titanium mesh, epidural hematoma, and seizures. In the computer-aided group, the operative time decreased (p < 0.01), the number of screws used was reduced (p < 0.01), and the satisfaction of patients was significantly increased (p < 0.05). CONCLUSIONS: Computer-aided shaping of titanium mesh for repairing large frontotemporoparietal skull defects decreases postoperative complications and the operative duration, reduces the number of screws used, increases the satisfaction of patients, and restores the appearance of the patient's head, making it an ideal choice for cranioplasty.

Digital evaluation of the reproducibility of implant scanbody fit--an in vitro study.

Dental restorations are increasingly manufactured by CAD/CAM systems. Currently, there are two alternatives for digitizing dental implants: direct intra-oral data capturing or indirect from a master cast, both with transfer caps (scanbodies). The aim of this study was the evaluation of the fit of the scanbodies and their ability of reposition. At the site of the first molars and canines, implants were placed bilaterally in a polymer lower arch model (original model), and an impression was taken for fabricating a stone cast (stone model). Ten white-light scans were obtained from the original and the stone model with the scanbodies in place. The scanbodies were retrieved after each scan and re-attached to the same implant or lab analogue. The first scan of the series served as control in both groups. The subsequent nine scans and control were superimposed using inspection software to identify the discrepancies of the four scanbodies in both experimental groups. The systematic error of digitizing the models was 13 µm for the polymer and 5 µm for the stone model. The mean discrepancy of the scanbodies was 39 µm (±58 µm) on the original implants versus 11 µm (±17 µm) on the lab analogues. The difference in scanbody discrepancy between original implants and lab analogues was statistically significant (p < 0.05, Mann-Whitney U test). Scanbody discrepancy was higher on original implants than on lab analogues. Fit and reproducibility of the scanbodies on original implants should be improved to achieve higher accuracy of implant-supported CAD/CAM fabricated restorations.