Factores de riesgo cardiometabólico y funcionamiento cognitivo: el rol de la reserva cognitiva / Association between cardiometabolic risk and cognitive impairment
Sepúlveda-Pezoa, Luciana; Gómez-Pérez, Daniela; Ortiz, Manuel S; Salinas-Rehbein, Belén; Cancino, Margarita.
Rev. méd. Chile
; 149(8): 1134-1140, ago. 2021. ilus
Artigo
em Espanhol
| LILACS | ID: biblio-1389574
Background:
Several risk factors are associated with cognitive impairment in older people, but little attention has been paid to cardiometabolic variables, as well as how cognitive reserve can mediate this association.Aim:
To determine the association of cardiometabolic risk factors with cognitive functioning and whether the cognitive reserve mediates this association. Material andMethods:
A cross-sectional study with 300 participants with a median age of 56 years (53% male) was conducted. Participants had a cognitive functioning assessment. Fasting glucose, HDL-cholesterol, and blood pressure were measured.Results:
A Structural Equation Modeling, revealed a direct effect of cardiometabolic latent risk factors on both a cognitive functioning (β = -.204; p = .056), and cognitive reserve factors (β = -.236, p = .04). Cognitive reserve was directly associated with cognitive functioning (β = .327, p = .01), but did not mediate the association between the cardiometabolic risk factors and cognitive functioning (β = .077, p = .07). The overall goodness of fitness was excellent χ2 (50) = 58.357, p = .195, comparative fit index = .980, Tucker-Lewis Index = .974, root mean square error of approximation = .023 and Standardized Root Mean Square Residual = .041.Conclusions:
A direct effect of cardiometabolic risk factors on cognitive functioning was observed.
Biblioteca responsável:
CL1.1
Texto completo
Documentos relacionados