Vancomycin-induced severe thrombocytopenia in a young infant
Chen, Quan-yao; Wan, Jun; Yang, Jian-hui; Lin, Min; Chen, Yao.
Rev. Soc. Bras. Med. Trop
; 51(6): 873-875, Nov.-Dec. 2018. tab, graf
Artigo
em Inglês
| LILACS | ID: biblio-977108
Abstract Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis. After 13 days of treatment with vancomycin, her platelet count reduced to 8 × 109/L. Vancomycin was discontinued, and intravenous methylprednisolone was administered. The platelet count returned to normal after 4 days. Patients, especially young children, receiving vancomycin for a long clinical course should undergo careful monitoring of laboratory indicators and blood tests.
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