Tumor-associated macrophages in cancers
Clin. transl. oncol. (Print)
; 18(3): 251-258, mar. 2016. tab, ilus
Article
em En
| IBECS
| ID: ibc-148708
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Tumor-associated macrophages (TAMs) are major component of leukocytic infiltrate of tumors and play important roles in progression and regression of tumors. Tumor microenvironment determines the mutual conversion between M1 and M2 macrophages. In many kinds of tumors, M2 type macrophages are of the majority in TAMs and promote tumor progression and metastasis. The dynamic balance and interaction between TAMs and tumor cells have important effects on the occurrence and development of tumor. TAMs in malignant tumors are useful for clinical diagnosis and may provide a novel target for cancer treatment (AU)
RESUMEN
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Base de dados:
IBECS
Assunto principal:
Neoplasias Gástricas
/
Lipopolissacarídeos
/
Helicobacter pylori
/
Carcinoma Hepatocelular
/
Proteínas Proto-Oncogênicas c-sis
/
Fatores de Necrose Tumoral
/
Análise do Polimorfismo de Comprimento de Fragmentos Amplificados
/
Leucócitos
/
Linfonodos
/
Macrófagos
Tipo de estudo:
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article