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Tetracycline and trimethoprim/sulfamethoxazole at clinical laboratory: Can they help to characterize Staphylococcus aureus carrying different SCCmec types?

Cavalcante, Fernanda Sampaio; Schuenck, Ricardo Pinto; Caboclo, Roberta Mello Ferreira; Ferreira, Dennis de Carvalho; Nouér, Simone Aranha; Santos, Kátia Regina Netto dos.
Rev. Soc. Bras. Med. Trop ; 46(1): 100-102, Jan.-Feb. 2013. tab
Artigo em Inglês | LILACS | ID: lil-666803

INTRODUCTION:

Methicillin-resistant Staphylococcus aureus (MRSA) can be difficult to detect at the clinical practice.

METHODS:

We analyzed 140 MRSA isolates from inpatients to correlate the antimicrobial susceptibility with the SCCmec types.

RESULTS:

Type III (n = 63) isolates were more resistant to ciprofloxacin, clindamycin, cloramphenicol, erythromycin, gentamicin, and rifampin than type IV (n = 65) ones (p < 0.05). Moreover, type IV isolates were susceptible to tetracycline (100%) and trimethoprim/sulfamethoxazole (98%), while type III isolates presented resistance to them.

CONCLUSIONS:

In regions where these SCCmec types are prevalent, the detection of specific resistant phenotypes could help to predict them, mainly when there are no technical conditions to SCCmec typing.
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