Follicular mucinosis associated with early stage cutaneous T-cell lymphoma: successful treatment with interferon alpha-2b and acitretin.
J Dermatolog Treat
; 12(2): 117-21, 2001 Jun.
Article
em En
| MEDLINE
| ID: mdl-12243671
ABSTRACT
BACKGROUND:
Follicular mucinosis (FM) is a rare dermatosis characterized by mucin deposits in the pilosebaceous units. It is divided into a primary-benign type and a secondary type associated mostly with lymphomas. No standard effective therapy is available for the primary FM while in the secondary form treatment is aimed against the underlying disease.METHODS:
We report a case of secondary FM in which a cutaneous T-cell lymphoma was detected 6 years after the initial eruption.RESULTS:
Complete remission was achieved with combination therapy of interferon alpha-2b at a dose of 6 million U subcutaneously three times a week, and acitretin 35 mg/day, for 6 months.CONCLUSION:
Regular clinical and histopathological evaluation is suggested for all patients with FM. For cases associated with cutaneous T-cell lymphoma the combination of interferon alpha and acitretin seems to be a good therapeutical approach.
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Base de dados:
MEDLINE
Assunto principal:
Síndromes Paraneoplásicas
/
Linfoma Cutâneo de Células T
/
Interferon-alfa
/
Acitretina
/
Mucinose Folicular
/
Ceratolíticos
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2001
Tipo de documento:
Article