The oral toxicity of clioquinol (5-chloro-7-iodo-8-hydroxyquinoline) in beagle dogs.
Toxicology
; 6(1): 41-6, 1976 Jun.
Article
em En
| MEDLINE
| ID: mdl-133475
ABSTRACT
When clioquinol was administered to Beagle dogs, disturbances in gait which were associated with abnormal reflexes and reactions, were seen in animals receiving 250 and 400 mg/kg body weight per day. Histopathological examination of the central nervous system (CNS) showed pathological change in the posterior columns of the spinal cord.
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Base de dados:
MEDLINE
Assunto principal:
Clioquinol
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article