Parental imprinting of the human H19 gene.
FEBS Lett
; 309(1): 25-8, 1992 Aug 31.
Article
em En
| MEDLINE
| ID: mdl-1380925
ABSTRACT
It has only recently become clear that genetic imprinting plays an important role in human embryogenesis and in processes leading to the development of pediatric cancers and other human diseases. Using a unique human tissue, the androgenetic complete hydatidiform mole, we established that the maternally inherited allele of the imprinted H19 gene is expressed. Our results also show that the paternal allele of the human IGF-II gene, a gene suspected to be parentally imprinted in humans, is expressed.
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Base de dados:
MEDLINE
Assunto principal:
Placenta
/
Neoplasias Uterinas
/
Coriocarcinoma
/
Mola Hidatiforme
/
Genes
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Ano de publicação:
1992
Tipo de documento:
Article