Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions.
AIDS
; 18(14): 1951-3, 2004 Sep 24.
Article
em En
| MEDLINE
| ID: mdl-15353981
ABSTRACT
In HIV-1-infected patients with long-term undetectable viraemia on highly active antiretroviral treatment (HAART), we found that pre-HAART plasma viraemia and the baseline proviral DNA level were significantly associated with the viraemia setpoint during scheduled treatment interruptions. In long-term treated patients, pre-HAART viraemia may not be available, and in these circumstances proviral DNA, measured at the time of scheduled treatment interruption, can help to identify patients likely to reach a low viraemia setpoint after treatment interruption.
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Base de dados:
MEDLINE
Assunto principal:
DNA Viral
/
Infecções por HIV
/
HIV-1
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article