Molecular characterization and drug resistance testing of Mycobacterium tuberculosis isolates from Chad.

Diguimbaye, Colette; Hilty, Markus; Ngandolo, Richard; Mahamat, Hassane H; Pfyffer, Gaby E; Baggi, Franca; Tanner, Marcel; Schelling, Esther; Zinsstag, Jakob

Diguimbaye, Colette; Hilty, Markus; Ngandolo, Richard; Mahamat, Hassane H; Pfyffer, Gaby E; Baggi, Franca; Tanner, Marcel; Schelling, Esther; Zinsstag, Jakob.

Afiliação

Diguimbaye C; Swiss Tropical Institute, Socinstrasse 57, P.O. Box CH 4002, Basel, Switzerland.

J Clin Microbiol ; 44(4): 1575-7, 2006 Apr.

Article em En | MEDLINE | ID: mdl-16597898

ABSTRACT

ABSTRACT

The molecular characterizations of the first 40 Mycobacterium tuberculosis isolates from Chad revealed a high proportion of isolates of the Cameroon family (33%), of which one isolate showed a monodrug resistance. In total, 9/33 (27%) isolates were resistant to isoniazid. The implications of these findings are discussed.

Assuntos

Antituberculosos/farmacologia; Farmacorresistência Bacteriana; Isoniazida/farmacologia; Mycobacterium tuberculosis/efeitos dos fármacos; Chade/epidemiologia; Humanos; Testes de Sensibilidade Microbiana; Mycobacterium tuberculosis/genética; Mycobacterium tuberculosis/isolamento & purificação

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Farmacorresistência Bacteriana / Isoniazida / Mycobacterium tuberculosis / Antituberculosos Limite: Humans País/Região como assunto: Africa Idioma: En Ano de publicação: 2006 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google