Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
Eur J Hum Genet
; 15(3): 260-3, 2007 Mar.
Article
em En
| MEDLINE
| ID: mdl-17164797
ABSTRACT
With the availability of dense maps of anonymous and frequent SNPs spanning the whole human genome, genome-wide association studies are now becoming a reality. In this paper, we discuss the utility of these approaches to detect genetic risk variants involved in complex disease susceptibility and, in the best case scenario where a signal is detected, how helpful it will be to the understanding of the pathological process.
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Base de dados:
MEDLINE
Assunto principal:
Genoma Humano
/
Predisposição Genética para Doença
/
Herança Multifatorial
/
Doenças Genéticas Inatas
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article