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Translocation (8;21) in two cases of refractory anemia with excess of blasts in transformation.
Maserati, E; Casali, M; Pasquali, F; Locatelli, F; Giani, S; Prete, L; Zecca, M; Invernizzi, R; Bassan, R.
Afiliação
  • Maserati E; Biologia Generale e Genetica Medica, Università di Pavia, Italy.
Cancer Genet Cytogenet ; 58(1): 76-8, 1992 Jan.
Article em En | MEDLINE | ID: mdl-1728955
We report two cases of refractory anemia with excess of blasts in transformation (RAEB-T) with the translocation (8;21), which is frequent in ANLL but not in myelodysplastic syndromes (MDS). A review of such cases leads us to conclude that myeloproliferative disorders characterized by the t(8;21) may be preceded by an MDS phase.
Assuntos
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Base de dados: MEDLINE Assunto principal: Translocação Genética / Cromossomos Humanos Par 8 / Cromossomos Humanos Par 21 / Anemia Refratária com Excesso de Blastos / Crise Blástica Limite: Child, preschool / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1992 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Translocação Genética / Cromossomos Humanos Par 8 / Cromossomos Humanos Par 21 / Anemia Refratária com Excesso de Blastos / Crise Blástica Limite: Child, preschool / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1992 Tipo de documento: Article