Cognitive decline and low blood pressure: the other side of the coin.
Clin Exp Hypertens
; 30(8): 711-9, 2008 Nov.
Article
em En
| MEDLINE
| ID: mdl-19021022
ABSTRACT
Low blood pressure has been found to be associated with cognitive decline and dementia in cross-sectional studies. Two mechanisms have been proposed to interpret this association blood pressure levels decrease during the course of the dementia process, and low blood pressure induces or accelerates cognitive decline by lowering cerebral blood flow. Results of the prospective studies are contradictory. Low blood pressure and orthostatic hypotension have been found to predict cognitive impairment in the elderly population in some studies only. While hypotension may play a protective role in healthy elderly people, low blood pressure levels in frail elderly patients with associated diseases may cause cerebral hypoperfusion and accelerate cognitive decline.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cognição
/
Hipotensão
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article