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Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.
Liu, Changlu; Wu, Jiejun; Zhu, Jessica; Kuei, Chester; Yu, Jingxue; Shelton, Jonathan; Sutton, Steven W; Li, Xiaorong; Yun, Su Jin; Mirzadegan, Taraneh; Mazur, Curt; Kamme, Fredrik; Lovenberg, Timothy W.
Afiliação
  • Liu C; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121. Electronic address: cliu9@its.jnj.com.
  • Wu J; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Zhu J; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Kuei C; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Yu J; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Shelton J; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Sutton SW; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Li X; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Yun SJ; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Mirzadegan T; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Mazur C; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Kamme F; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
  • Lovenberg TW; Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121.
J Biol Chem ; 284(5): 2811-2822, 2009 Jan 30.
Article em En | MEDLINE | ID: mdl-19047060
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adipócitos / Ácido Láctico / Receptores Acoplados a Proteínas G / Lipólise Limite: Animals / Humans Idioma: En Ano de publicação: 2009 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adipócitos / Ácido Láctico / Receptores Acoplados a Proteínas G / Lipólise Limite: Animals / Humans Idioma: En Ano de publicação: 2009 Tipo de documento: Article