DNA Cytosine demethylation: are we getting close?
Cell
; 135(7): 1167-9, 2008 Dec 26.
Article
em En
| MEDLINE
| ID: mdl-19109887
ABSTRACT
Whether 5-methylcytosine (meC) can be enzymatically removed from vertebrate DNA has been the subject of extensive study and also some controversy. Rai et al. (2008) now report that cytosine demethylation can be accomplished in a one-cell zebrafish embryo by the combined action of a cytidine deaminase and a thymine DNA glycosylase.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Metilação de DNA
/
Citosina
Limite:
Animals
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article