[CNS-active substances: synthesis of epoxybenzoxocines]. / ZNS-Wirkstoffe: Synthese von Epoxybenzoxocinen.
Arch Pharm (Weinheim)
; 323(11): 933-6, 1990 Nov.
Article
em De
| MEDLINE
| ID: mdl-2080900
ABSTRACT
The 2-(2-Bromophenyl)-acetaldehyde acetals 8 are treated with n-BuLi and the aldehydes 7 and 11 to form the hydroxyacetales 9 and 12, respectively. 9 is cyclized under acidic conditions to the epoxybenzoxocine 2; analogously 12 yields the epoxydibenzoxocine 14.
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MEDLINE
Assunto principal:
Compostos Bicíclicos com Pontes
/
Fármacos do Sistema Nervoso Central
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Compostos de Epóxi
Idioma:
De
Ano de publicação:
1990
Tipo de documento:
Article