[Osteogenic and tracking study of bone marrow stromal stem cells in vivo].
Zhonghua Yi Xue Za Zhi
; 90(37): 2652-6, 2010 Oct 12.
Article
em Zh
| MEDLINE
| ID: mdl-21162936
ABSTRACT
OBJECTIVE:
To detect and track the presence of magnetically labeled bone marrow stromal cells (MSCs) in vivo with magnetic resonance imaging (MRI) after autologous transplantation.METHODS:
The cultured and SPIO-labeled MSCs were transplanted into dog femoral head. The dog received regular MRI re-examination at post-operation. Samples were harvested at different weeks for analysis.RESULTS:
The labeled cells showed an obviously low intensity of signal change in MRI. There were lots of labeled cells in the transplant area and more bone formation than the controls.CONCLUSION:
The labeled cells can be visualized in vivo by MRI examination after transplantation into femoral head. The transplanted MSCs survive in vivo and increase bone formation.
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Base de dados:
MEDLINE
Assunto principal:
Células da Medula Óssea
/
Imageamento por Ressonância Magnética
/
Durapatita
/
Células-Tronco Mesenquimais
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2010
Tipo de documento:
Article