Alveolar rhabdomyosarcoma originating from the uterine cervix.
Eur J Gynaecol Oncol
; 32(2): 196-8, 2011.
Article
em En
| MEDLINE
| ID: mdl-21614913
ABSTRACT
Cervical alveolar rhabdomyosarcoma is a rare condition associated with poor prognosis. An 18-year-old patient presented with vaginal bleeding and a protruding mass from the vagina. Biopsy of the mass revealed alveoler rhabdomyosarcoma (ARMS), and radiological evaluation demonstrated that it originated from the uterine cervix. First, Wertheim's operation was carried out followed by four cycles of vincristine, actinomycine-D, ifosfamide (VAI) chemotherapy. However, the disease relapsed within three months, and the patient died of disease progression. Despite combination treatment, we could not achieve a desirable survival advantage in ARMS. Future studies may unveil the genomic profile of this rare condition, leading to invention of targeted therapies, which is the emerging trend in the treatment of sarcomas.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo do Útero
/
Rabdomiossarcoma Alveolar
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article