The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae.
Mol Cell Biol
; 10(5): 2437-41, 1990 May.
Article
em En
| MEDLINE
| ID: mdl-2183035
ABSTRACT
The same factor, ABF1, binds to the promoters of the two gene copies (L2A and L2B) coding for the ribosomal protein L2 in Saccharomyces cerevisiae. In vitro binding experiments and in vivo functional analysis showed that the different affinities of the L2A and L2B promoters for the ABF1 factor are responsible for the differential transcriptional activities of the two gene copies. The presence of ABF1-binding sites in front of many housekeeping genes suggests a general role for ABF1 in the regulation of gene activity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas Ribossômicas
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Saccharomyces cerevisiae
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Fatores de Transcrição
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Sequências Reguladoras de Ácido Nucleico
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article