Strong correlation between liver and serum levels of hepatitis C virus core antigen and RNA in chronically infected patients.
J Clin Microbiol
; 50(2): 465-8, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22162563
ABSTRACT
HCV core antigen (Ag) and HCV RNA levels were evaluated in matched liver biopsy samples and sera from 22 patients with hepatitis C infection by using the quantitative Architect HCV Ag immunoassay and a real-time RT-qPCR assay, respectively. The data showed a strong correlation between liver and serum compartments of HCV Ag levels (r = 0.80) and HCV RNA levels (r = 0.87). In summary, the serum HCV Ag and RNA levels reflect the intrahepatic values.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
RNA Viral
/
Proteínas do Core Viral
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Hepacivirus
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Hepatite C Crônica
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Soro
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Fígado
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article